FRK

Gene Symbol	FRK
Entrez Gene	2444
Alt Symbol	GTK, PTK5, RAK
Species	Human
Gene Type	protein-coding
Description	fyn-related Src family tyrosine kinase
Other Description	PTK5 protein tyrosine kinase 5|fyn-related kinase|nuclear tyrosine protein kinase RAK|protein-tyrosine kinase 5|tyrosine-protein kinase FRK
Swissprots	P42685 Q9NTR5 B4DY49 Q13128
Accessions	EAW48241 P42685 AK302264 BAG63611 AK313314 BAG36119 BC012916 AAH12916 DQ894643 ABM85569 U00803 AAA18284 U22322 AAC50116 XM_005266880 XP_005266937 XM_005266881 XP_005266938 XM_005266882 XP_005266939 XM_011535653 XP_011533955 XM_011535654 XP_011533956 XM_011535655 XP_011533957 XM_011535656 XP_011533958 NM_002031 NP_002022
Function	Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor. {ECO:0000269|PubMed:19345329}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:7696183}. Nucleus {ECO:0000269|PubMed:7696183}. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery.
Tissue Specificity	Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon. {ECO:0000269|PubMed:7696183}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active FRK protein fragment - ab60861 from Abcam Category Protein Prices $294.00, $1,845.00 Sizes 10 µg, 100 µg Source Baculovirus infected sf9 cells

Human FRK full length protein - ab131807 from Abcam Category Protein Source Wheat germ Species Human

Human FRK protein fragment - ab152399 from Abcam Category Protein Source Wheat germ Species Human

FRK Antibody Blocking Peptide - LS-E3640 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FRK Antibody Blocking Peptide - LS-E19677 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FRK Antibody Blocking Peptide - LS-E19676 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Frk Recombinant Protein - H00002444-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

Frk Partial Recombinant Protein - H00002444-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Frk Recombinant Protein - P4246 from Novus Biologicals Category Protein Prices $549.00 Sizes 5 µg Species Human

Frk Recombinant Protein - P3864 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 5 µg Species Human

Recombinant Human Frk Protein - P4696 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Source Insect Species Human

Recombinant Frk Protein - NBP1-99510 from Novus Biologicals Category Protein Prices $295.00 Sizes 5 µg Source Baculovirus (Sf9 insect cells)

FRK (Active) recombinant protein - GTX65098 from GeneTex Category Protein Prices $329.00 Sizes 5 μg Source Baculovirus (Sf9 insect cells) Species Human

FRK Blocking Peptide - 33R-2066 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FRK Blocking Peptide - 33R-4832 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FRK protein - 30R-2877 from Fitzgerald Category Protein Prices $375.00 Sizes 5 µg Source Sf-9 insect cells Species Human

FRK Blocking Peptide - abx062636 from Abbexa Category Peptide Species Human, Rat

FRK / PTK5 - H00002444-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

FRK / PTK5 - H00002444-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FRK / PTK5 - P3864 from Acris Antibodies Category Protein Prices $1,230.00 Sizes 5 µg Species Human

FRK / PTK5 - P4246 from Acris Antibodies Category Protein Prices $670.00 Sizes 5 µg Species Human

FRK / PTK5 - P4696 from Acris Antibodies Category Protein Prices $1,380.00 Sizes 100 µg Species Human

FRK fusion protein - Ag0510 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

FRK fusion protein - Ag10024 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

FRK fusion protein - ag10372 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Search more