| Gene Symbol | TAPBPL |
|---|---|
| Entrez Gene | 55080 |
| Alt Symbol | TAPBP-R, TAPBPR |
| Species | Human |
| Gene Type | protein-coding |
| Description | TAP binding protein-like |
| Other Description | TAP binding protein related|TAP-binding protein-like|TAP-binding protein-related protein|TAPASIN-R|tapasin-like|tapasin-related protein |
| Swissprots | Q9NWB8 Q9BX59 |
| Accessions | CAI93432 EAW88797 EAW88798 EAW88799 Q9BX59 AI184901 AI273155 AK001005 BAA91465 AK002056 BAB41077 AK098035 AK222956 BAD96676 AK223163 BAD96883 BC015017 AAH15017 CR997450 DB054664 HQ258015 ADR82769 XM_005253699 XP_005253756 XM_005253700 XP_005253757 XM_005253701 XP_005253758 XM_005253702 XP_005253759 XM_005253703 XP_005253760 XM_011520966 XP_011519268 XR_429016 NM_018009 NP_060479 |
| Function | Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2- microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC). Expression seems to slow down and down-regulate MHC class I surface expression. {ECO:0000269|PubMed:23401559}. |
| Subcellular Location | Cell membrane {ECO:0000305|PubMed:11920573}; Single-pass type I membrane protein {ECO:0000305|PubMed:11920573}. Endoplasmic reticulum membrane {ECO:0000305|PubMed:11920573}; Single-pass type I membrane protein {ECO:0000305|PubMed:11920573}. Microsome membrane {ECO:0000305|PubMed:11920573}; Single-pass type I membrane protein {ECO:0000305|PubMed:11920573}. Golgi apparatus membrane {ECO:0000269|PubMed:23401559}; Single-pass type I membrane protein. Note=Mainly found in endoplasmic reticulum but a minority is found on the cell surface. |
TAPBPL (Human) Matched Antibody Pair - H00055080-AP51 from Acris Antibodies
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TAP binding protein-like, ELISA Kit - MBS9327810 from MyBioSource
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Human TAPBPL ELISA Kit - E101119 from Biobool
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Human Tapasin-related protein (TAPBPL) ELISA Kit - AE16429HU from ARP American Research Products
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