Gene Symbol | TAPBPL |
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Entrez Gene | 55080 |
Alt Symbol | TAPBP-R, TAPBPR |
Species | Human |
Gene Type | protein-coding |
Description | TAP binding protein-like |
Other Description | TAP binding protein related|TAP-binding protein-like|TAP-binding protein-related protein|TAPASIN-R|tapasin-like|tapasin-related protein |
Swissprots | Q9NWB8 Q9BX59 |
Accessions | CAI93432 EAW88797 EAW88798 EAW88799 Q9BX59 AI184901 AI273155 AK001005 BAA91465 AK002056 BAB41077 AK098035 AK222956 BAD96676 AK223163 BAD96883 BC015017 AAH15017 CR997450 DB054664 HQ258015 ADR82769 XM_005253699 XP_005253756 XM_005253700 XP_005253757 XM_005253701 XP_005253758 XM_005253702 XP_005253759 XM_005253703 XP_005253760 XM_011520966 XP_011519268 XR_429016 NM_018009 NP_060479 |
Function | Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2- microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC). Expression seems to slow down and down-regulate MHC class I surface expression. {ECO:0000269|PubMed:23401559}. |
Subcellular Location | Cell membrane {ECO:0000305|PubMed:11920573}; Single-pass type I membrane protein {ECO:0000305|PubMed:11920573}. Endoplasmic reticulum membrane {ECO:0000305|PubMed:11920573}; Single-pass type I membrane protein {ECO:0000305|PubMed:11920573}. Microsome membrane {ECO:0000305|PubMed:11920573}; Single-pass type I membrane protein {ECO:0000305|PubMed:11920573}. Golgi apparatus membrane {ECO:0000269|PubMed:23401559}; Single-pass type I membrane protein. Note=Mainly found in endoplasmic reticulum but a minority is found on the cell surface. |
Human Tapasin Related Protein full length protein - ab132118 from Abcam
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Human Tapasin Related Protein peptide - ab23226 from Abcam
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Human Tapasin Related Protein protein fragment - ab153392 from Abcam
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TAPBPL / TAPBPR Antibody Blocking Peptide - LS-E4176 from LifeSpan Bioscience
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TAPBPL / TAPBPR Antibody Blocking Peptide - LS-E17176 from LifeSpan Bioscience
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Recombinant Human Tapasin Related Protein Protein - H00055080-Q01 from Novus Biologicals
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Recombinant Human Tapasin Related Protein Protein - H00055080-P01 from Novus Biologicals
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TAPBPL-Antibody-N-term-Blocking-Peptide - BP16431a from Abgent, a WuXi AppTec company
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TAPBPL blocking peptide - GTX13673-PEP from GeneTex
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Tapasin-related protein (TAPBPL) - H00055080-P01-10 from Acris Antibodies
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Tapasin-related protein (TAPBPL) - H00055080-P01-25 from Acris Antibodies
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Tapasin-related protein (TAPBPL) - H00055080-Q01-10 from Acris Antibodies
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Tapasin-related protein (TAPBPL) - H00055080-Q01-25 from Acris Antibodies
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TAPBPL fusion protein - ag14371 from Proteintech Group
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Recombinant Human Tapasin-related protein(TAPBPL) - CSB-YP887144HU CSB-EP887144HU CSB-BP887144HU CSB-MP887144HU from Cusabio
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Tapasin-related protein (TAPBPL) - TP301899 from Acris Antibodies
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Tapasin-related protein (TAPBPL), Recombinant Protein - MBS1397395 from MyBioSource
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Tapasin Related Protein Recombinant Protein Antigen - NBP1-87922PEP from Novus Biologicals
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TAPBPL Peptide, Human - M34GP15579H from Creative Peptides
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