CRK

Gene Symbol	CRK
Entrez Gene	1398
Alt Symbol	CRKII, p38
Species	Human
Gene Type	protein-coding
Description	v-crk avian sarcoma virus CT10 oncogene homolog
Other Description	adapter molecule crk|proto-oncogene c-Crk
Swissprots	Q96HJ0 A8MWE8 Q96GA9 D3DTH6 B0LPE8 P46108
Accessions	AAB28213 ABY87527 AGC09588 EAW90621 EAW90622 EAW90623 EAW90624 EAW90625 EAW90626 P46108 AK095449 AK291060 BAF83749 AU125411 BC001718 AAH01718 BC008506 AAH08506 BC009837 AAH09837 BT007277 AAP35941 D10656 BAA01505 DQ891147 ABM82073 DQ894327 ABM85253 NM_005206 NP_005197 NM_016823 NP_058431
Function	The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling. {ECO:0000269|PubMed:11870224, ECO:0000269|PubMed:1630456, ECO:0000269|PubMed:17515907}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocated to the plasma membrane upon cell adhesion. {ECO:0000250}.
Top Pathways	Rap1 signaling pathway, Bacterial invasion of epithelial cells, Chemokine signaling pathway, MicroRNAs in cancer, Focal adhesion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat Phospho-CRK (Tyr221) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1082 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat CRK ELISA Kit (Cell-Based ELISA) - LS-F1913 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Adapter molecule crk (CRK), Human, ELISA Kit - E01A1816 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Adapter molecule crk, CRK, Human, ELISA Kit - E9658h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t

CrkII Colorimetric Cell-Based ELISA Kit - CB5171 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

CrkII (Phospho-Tyr221) Colorimetric Cell-Based ELISA Kit - CBP1059 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Adapter molecule crk (CRK), ELISA Kit - MBS7246357 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Adapter molecule crk (CRK), ELISA Kit - MBS7201819 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Adapter molecule crk (CRK), ELISA Kit - MBS7235420 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Adapter molecule crk (CRK), ELISA Kit - MBS7215474 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Adapter molecule crk (CRK), ELISA Kit - MBS7201414 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Adapter molecule crk (CRK), ELISA Kit - MBS7221383 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Adapter molecule crk (CRK), ELISA Kit - MBS7210382 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Adapter molecule crk (CRK), ELISA Kit - MBS7203728 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

Adapter molecule crk (CRK), ELISA Kit - MBS7229887 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Adapter molecule crk (CRK), ELISA Kit - MBS7215049 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Adapter molecule crk (CRK), ELISA Kit - MBS7239125 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Adapter molecule crk (CRK), ELISA Kit - MBS7220723 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human CRK ELISA Kit (Custom ELISA) - LS-F20515 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Chicken CRK ELISA Kit (Custom ELISA) - LS-F20513 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Rat CRK ELISA Kit (Custom ELISA) - LS-F20514 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Mouse CRK ELISA Kit (Sandwich ELISA) - LS-F13139 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

CrkII ELISA Kit - DEIA-XYA474 from Creative Diagnostics Category ELISA Kit

CrkII (Phospho-Tyr221) ELISA Kit - DEIA-XYA475 from Creative Diagnostics Category ELISA Kit

Human CRK ELISA Kit - E000719 from Biobool Category ELISA Kit Sensitivity 1.0 pg/mL.

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