CRK

Gene Symbol	CRK
Entrez Gene	1398
Alt Symbol	CRKII, p38
Species	Human
Gene Type	protein-coding
Description	v-crk avian sarcoma virus CT10 oncogene homolog
Other Description	adapter molecule crk|proto-oncogene c-Crk
Swissprots	Q96HJ0 A8MWE8 Q96GA9 D3DTH6 B0LPE8 P46108
Accessions	AAB28213 ABY87527 AGC09588 EAW90621 EAW90622 EAW90623 EAW90624 EAW90625 EAW90626 P46108 AK095449 AK291060 BAF83749 AU125411 BC001718 AAH01718 BC008506 AAH08506 BC009837 AAH09837 BT007277 AAP35941 D10656 BAA01505 DQ891147 ABM82073 DQ894327 ABM85253 NM_005206 NP_005197 NM_016823 NP_058431
Function	The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling. {ECO:0000269|PubMed:11870224, ECO:0000269|PubMed:1630456, ECO:0000269|PubMed:17515907}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocated to the plasma membrane upon cell adhesion. {ECO:0000250}.
Top Pathways	Rap1 signaling pathway, Bacterial invasion of epithelial cells, Chemokine signaling pathway, MicroRNAs in cancer, Focal adhesion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CRK gene - orb92532 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-CRK-cDNA-Clone - DC02791 from Abgent, a WuXi AppTec company Prices $275.40 Sizes 10 µg Species Human Accession BC009837

CRK cDNA (ANA10281) - ANA10281 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC008506

CRK cDNA (ANA10439) - ANA10439 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC008506

CRK cDNA (ANA11138) - ANA11138 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC008506

CRK - MBS1269537 from MyBioSource Species Human Accession BC009837

CRK - MBS1273408 from MyBioSource Species Human Accession BC008506

Human CRK ORF Clone(NM_016823.3) - CDCL159767 from Creative Biomart Species Human Accession NM_016823.3

Human CRK ORF Clone(NM_005206.4) - CDCL159768 from Creative Biomart Species Human Accession NM_005206.4

Human CRK Gene cDNA Clone (full-length ORF Clone) - HG12002-M from Sino Biological Species Human Accession NM_016823.2

Human CRK Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-tagged - HG12002-CH from Sino Biological Species Human Accession NM_016823.2

Human CRK Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG12002-UT from Sino Biological Species Human Accession NM_016823.2

Human CRK natural ORF mammalian expression plasmid, C-GFPSpark tag - HG12002-ACG from Sino Biological Species Human Accession NM_016823.2

Human CRK Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-tagged - HG12002-CY from Sino Biological Species Human Accession NM_016823.2

Human CRK Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-tagged - HG12002-NF from Sino Biological Species Human Accession NM_016823.2

Human CRK natural ORF mammalian expression plasmid, N-HA tag - HG12002-NY from Sino Biological Species Human Accession NM_016823.2

Human CRK natural ORF mammalian expression plasmid, C-OFPSpark / RFP tag - HG12002-ACR from Sino Biological Species Human Accession NM_016823.2

Human CRK Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG12002-M-F from Sino Biological Species Human Accession NM_016823.2

Human CRK Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG12002-M-N from Sino Biological Species Human Accession NM_016823.2

Human CRK Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG12497-G-N from Sino Biological Species Human Accession BC008506

Human CRK Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-tagged - HG12002-NH from Sino Biological Species Human Accession NM_016823.2

Human CRK Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-tagged - HG12002-CF from Sino Biological Species Human Accession NM_016823.2

Human CRK Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-tagged - HG12002-NM from Sino Biological Species Human Accession NM_016823.2

Human CRK Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-tagged - HG12002-CM from Sino Biological Species Human Accession NM_016823.2

Human CRK ORF Clone (BC009837) - CDCS412140 from Creative biogene Species Human Accession P46108

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