Gene Symbol | CCDC8 |
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Entrez Gene | 83987 |
Alt Symbol | 3M3, PPP1R20, p90 |
Species | Human |
Gene Type | protein-coding |
Description | coiled-coil domain containing 8 |
Other Description | coiled-coil domain-containing protein 8|protein phosphatase 1, regulatory subunit 20 |
Swissprots | Q9H0W5 Q8TB26 |
Accessions | EAW57418 Q9H0W5 AI301367 AK297668 BAG60030 AL136609 CAB66544 BC015648 BC025243 AAH25243 BG717344 BX096201 EU831718 ACE86552 JN703457 AET25567 NM_032040 NP_114429 |
Function | Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (PubMed:24793695, PubMed:24793696). Required for localization of CUL7 to the centrosome (PubMed:24793695). {ECO:0000269|PubMed:24793695, ECO:0000269|PubMed:24793696}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:24793695}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:24793695}. |
Tissue Specificity | Widely expressed with low levels in spleen, skeletal muscle, small intestine, kidney and liver. {ECO:0000269|PubMed:21737058}. |
CCDC8 Antibody Blocking Peptide - LS-E309 from LifeSpan Bioscience
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CCDC8-Antibody-C-term-Blocking-Peptide - BP10554b from Abgent, a WuXi AppTec company
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Recombinant Human Coiled-coil domain-containing protein 8(CCDC8) - CSB-YP880938HU CSB-EP880938HU CSB-BP880938HU CSB-MP880938HU from Cusabio
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CCDC8 Recombinant Protein Antigen - NBP1-85085PEP from Novus Biologicals
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CCDC8 Peptide, Human - M34GP02580H from Creative Peptides
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CCDC8 fusion protein - Ag25794 from Proteintech Group
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Coiled-coil domain-containing protein 8 (CCDC8), Recombinant Protein - MBS1475350 from MyBioSource
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