CCDC8

Gene Symbol CCDC8
Entrez Gene 83987
Alt Symbol 3M3, PPP1R20, p90
Species Human
Gene Type protein-coding
Description coiled-coil domain containing 8
Other Description coiled-coil domain-containing protein 8|protein phosphatase 1, regulatory subunit 20
Swissprots Q9H0W5 Q8TB26
Accessions EAW57418 Q9H0W5 AI301367 AK297668 BAG60030 AL136609 CAB66544 BC015648 BC025243 AAH25243 BG717344 BX096201 EU831718 ACE86552 JN703457 AET25567 NM_032040 NP_114429
Function Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (PubMed:24793695, PubMed:24793696). Required for localization of CUL7 to the centrosome (PubMed:24793695). {ECO:0000269|PubMed:24793695, ECO:0000269|PubMed:24793696}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:24793695}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:24793695}.
Tissue Specificity Widely expressed with low levels in spleen, skeletal muscle, small intestine, kidney and liver. {ECO:0000269|PubMed:21737058}.

CCDC8 CRISPR/Cas9 KO Plasmid (h) - sc-406749 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC8 HDR Plasmid (h) - sc-406749-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC8 Double Nickase Plasmid (h) - sc-406749-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC8 Double Nickase Plasmid (h2) - sc-406749-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC8 CRISPR Activation Plasmid (h) - sc-406749-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC8 CRISPR Activation Plasmid (h2) - sc-406749-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC8 Lentiviral Activation Particles (h) - sc-406749-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC8 Lentiviral Activation Particles (h2) - sc-406749-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC8 siRNA (h) - sc-97657 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CCDC8 shRNA Plasmid (h) - sc-97657-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CCDC8 shRNA (h) Lentiviral Particles - sc-97657-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU154711 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5567 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5567 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03222 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03222

CCDC8 siRNA (Human) - CRJ3258 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CCDC8 - MBS8217981 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CCDC8 CRISPR/Cas9 KO Plasmid (h2) - sc-406749-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC8 HDR Plasmid (h2) - sc-406749-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human CCDC8 (NM_032040.4) - SHH257125 from Creative biogene

Category siRNA
Species Reactivities Human

Human CCDC8 siRNA - orb273759 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CCDC8 shRNA Plasmid (Human) - CHJ3258 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CCDC8 miRNA 3'UTR clone - MiUTR3H-13151 from Creative biogene

Species Reactivities Human
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