Gene Symbol | ACOT4 |
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Entrez Gene | 122970 |
Alt Symbol | PTE-Ib, PTE1B, PTE2B |
Species | Human |
Gene Type | protein-coding |
Description | acyl-CoA thioesterase 4 |
Other Description | PTE-2b|acyl-coenzyme A thioesterase 4|peroxisomal acyl coenzyme A thioester hydrolase Ib|peroxisomal acyl-CoA thioesterase 2B|peroxisomal long-chain acyl-CoA thioesterase Ib |
Swissprots | Q86TX1 Q96N88 Q17RF4 Q5BKT6 Q8N9L9 Q86TX0 |
Accessions | EAW81120 EAW81121 Q8N9L9 AK055797 BAB71017 AK094223 BAC04313 BC031799 AAH31799 BC090945 AAH90945 BC117341 AAI17342 BC117343 AAI17344 BX248023 CAD62346 BX248047 CAD62354 NM_152331 NP_689544 |
Function | Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs. {ECO:0000250}. |
Subcellular Location | Peroxisome {ECO:0000269|PubMed:16940157}. |
Tissue Specificity | Strongest expression in liver and kidney and weaker expression in placenta, heart, and muscle. {ECO:0000269|PubMed:16940157}. |
Top Pathways | Fatty acid elongation, Biosynthesis of unsaturated fatty acids |
ACOT4 (P-13) - sc-82484 from Santa Cruz Biotechnology
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Anti-Acyl-coenzyme A Thioesterase 4 antibody - ab121116 from Abcam
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Anti-Acyl-coenzyme A Thioesterase 4 antibody - ab134984 from Abcam
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Anti-ACOT4 Antibody (aa297-345) - LS-C186701 from LifeSpan Bioscience
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Anti-ACOT4 Antibody (aa351-400) - LS-C200080 from LifeSpan Bioscience
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Anti-ACOT4 Antibody (aa361-410) - LS-C119694 from LifeSpan Bioscience
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ACOT4 Antibody - NBP1-83539 from Novus Biologicals
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Anti-ACOT4 antibody produced in rabbit - HPA000779 from Sigma-Aldrich
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ACOT4 Antibody - middle region (ARP58412_P050) - ARP58412_P050 from Aviva Systems Biology
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ACOT4 antibody - GTX87881 from GeneTex
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ACOT4 Antibody (OAAF03229) - OAAF03229 from Aviva Systems Biology
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ACOT4 Antibody (OAAF06047) - OAAF06047 from Aviva Systems Biology
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ACOT4 antibody - 70R-33991 from Fitzgerald
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ACOT4 Antibody - abx014150 from Abbexa
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ACOT4 antibody - 17316-1-AP from Proteintech Group
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Anti-ACOT4 antibody - STJ91453 from St John's Laboratory Ltd
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ACOT4 - MBS2523150 from MyBioSource
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ACOT4 Polyclonal Antibody - PA000640-C14272 from Syd Labs
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ACOT4 Polyclonal Antibody - PA000640-R12-2439 from Syd Labs
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ACOT4 Antibody - 34382 from Signalway Antibody
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ACOT4 Antibody - E11-14272C from Enogene
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ACOT4 Antibody - C14272 from Assay Biotechnology
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ACOT4 Antibody - R12-2439 from Assay Biotechnology
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Human ACOT4 Antibody - GWB-ASE321 from Genway Biotech
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ACOT4 Antibody - EPP10095 from Elabscience
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