Gene Symbol | ACOT4 |
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Entrez Gene | 122970 |
Alt Symbol | PTE-Ib, PTE1B, PTE2B |
Species | Human |
Gene Type | protein-coding |
Description | acyl-CoA thioesterase 4 |
Other Description | PTE-2b|acyl-coenzyme A thioesterase 4|peroxisomal acyl coenzyme A thioester hydrolase Ib|peroxisomal acyl-CoA thioesterase 2B|peroxisomal long-chain acyl-CoA thioesterase Ib |
Swissprots | Q86TX1 Q96N88 Q17RF4 Q5BKT6 Q8N9L9 Q86TX0 |
Accessions | EAW81120 EAW81121 Q8N9L9 AK055797 BAB71017 AK094223 BAC04313 BC031799 AAH31799 BC090945 AAH90945 BC117341 AAI17342 BC117343 AAI17344 BX248023 CAD62346 BX248047 CAD62354 NM_152331 NP_689544 |
Function | Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs. {ECO:0000250}. |
Subcellular Location | Peroxisome {ECO:0000269|PubMed:16940157}. |
Tissue Specificity | Strongest expression in liver and kidney and weaker expression in placenta, heart, and muscle. {ECO:0000269|PubMed:16940157}. |
Top Pathways | Fatty acid elongation, Biosynthesis of unsaturated fatty acids |
ACOT4 Antibody Blocking Peptide - LS-E21360 from LifeSpan Bioscience
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ACOT4-Antibody-N-term-Blocking-peptide - BP10169a from Abgent, a WuXi AppTec company
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ACOT4-Antibody-C-term-Blocking-peptide - BP12844b from Abgent, a WuXi AppTec company
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ACOT4 fusion protein - ag11286 from Proteintech Group
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ACOT4 fusion protein - Ag11271 from Proteintech Group
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ACOT4 Blocking Peptide - CBP3454 from Cohesion Biosciences
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Recombinant Human Acyl-coenzyme A thioesterase 4(ACOT4) - CSB-YP822738HU CSB-EP822738HU CSB-BP822738HU CSB-MP822738HU from Cusabio
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Acyl-coenzyme A thioesterase 4(ACOT4) - MBS1411831 from MyBioSource
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ACOT4 - TP310550 from Acris Antibodies
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ACOT4 Blocking Peptide - abx162316 from Abbexa
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ACOT4 Recombinant Protein Antigen - NBP1-83539PEP from Novus Biologicals
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ACOT4 Peptide, Human - M34GP00145H from Creative Peptides
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ACOT4 Peptide - orb224340 from Biorbyt
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