Gene Symbol | LRSAM1 |
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Entrez Gene | 90678 |
Alt Symbol | CMT2P, RIFLE, TAL |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat and sterile alpha motif containing 1 |
Other Description | E3 ubiquitin-protein ligase LRSAM1|Tsg101-associated ligase |
Swissprots | Q6UWE0 Q5VVV0 Q96MZ7 Q96GT5 Q96MX5 Q8NB40 |
Accessions | EAW87671 EAW87672 EAW87673 EAW87674 Q6UWE0 AF086398 AI364608 AK056203 BAB71119 AK056305 BAB71144 AK091589 BAC03703 AK097094 AK226106 AY358830 AAQ89189 BC009239 AAH09239 DA165729 DA393757 DA726792 DB165274 DB309230 Z44095 XM_006717316 XP_006717379 XR_929874 NM_001005373 NP_001005373 NM_001005374 NP_001005374 NM_001190723 NP_001177652 NM_138361 NP_612370 |
Function | E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. {ECO:0000269|PubMed:15256501}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15256501}. Note=Displays a punctuate distribution and localizes to a submembranal ring. |
Tissue Specificity | Highly expressed in adult spinal cord motoneurons as well as in fetal spinal cord and muscle tissue. {ECO:0000269|PubMed:22012984}. |
LRSAM1 Antibody - 14400 from Cell Signaling Technology
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LRSAM1 (C-17) - sc-139531 from Santa Cruz Biotechnology
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LRSAM1 (E-20) - sc-139529 from Santa Cruz Biotechnology
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LRSAM1 (K-16) - sc-139530 from Santa Cruz Biotechnology
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Anti-LRSAM1 antibody - ab73113 from Abcam
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Anti-LRSAM1 antibody - ab103677 from Abcam
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Anti-LRSAM1 antibody - N-terminal - ab171556 from Abcam
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Anti-LRSAM1 Antibody (N-Terminus) - LS-C345278 from LifeSpan Bioscience
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Anti-LRSAM1 Antibody (aa1-30) - LS-C165899 from LifeSpan Bioscience
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Anti-LRSAM1 Antibody (aa1-30, APC) - LS-C262301 from LifeSpan Bioscience
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Anti-LRSAM1 Antibody (aa1-30, AP) - LS-C262302 from LifeSpan Bioscience
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Anti-LRSAM1 Antibody (aa1-30, Biotin) - LS-C262303 from LifeSpan Bioscience
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Anti-LRSAM1 Antibody (aa1-30, FITC) - LS-C262304 from LifeSpan Bioscience
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Anti-LRSAM1 Antibody (aa1-30, Azide-free, HRP) - LS-C262305 from LifeSpan Bioscience
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Anti-LRSAM1 Antibody (aa1-30, PE) - LS-C262308 from LifeSpan Bioscience
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Anti-LRSAM1 Antibody - LS-C308823 from LifeSpan Bioscience
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Anti-LRSAM1 Antibody - LS-C310900 from LifeSpan Bioscience
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Anti-LRSAM1 Antibody - LS-C310902 from LifeSpan Bioscience
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Anti-LRSAM1 Antibody (aa1-30) - LS-C322753 from LifeSpan Bioscience
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LRSAM1 Antibody - NBP1-82016 from Novus Biologicals
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LRSAM1 Antibody - NBP1-82017 from Novus Biologicals
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LRSAM1 Antibody - H00090678-D01P from Novus Biologicals
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LRSAM1 Antibody - H00090678-D01 from Novus Biologicals
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LRSAM1 Polyclonal Antibody - bs-9387R from Bioss
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Anti-LRSAM1 antibody produced in mouse - SAB1408175 from Sigma-Aldrich
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