LRSAM1

Gene Symbol	LRSAM1
Entrez Gene	90678
Alt Symbol	CMT2P, RIFLE, TAL
Species	Human
Gene Type	protein-coding
Description	leucine rich repeat and sterile alpha motif containing 1
Other Description	E3 ubiquitin-protein ligase LRSAM1|Tsg101-associated ligase
Swissprots	Q6UWE0 Q5VVV0 Q96MZ7 Q96GT5 Q96MX5 Q8NB40
Accessions	EAW87671 EAW87672 EAW87673 EAW87674 Q6UWE0 AF086398 AI364608 AK056203 BAB71119 AK056305 BAB71144 AK091589 BAC03703 AK097094 AK226106 AY358830 AAQ89189 BC009239 AAH09239 DA165729 DA393757 DA726792 DB165274 DB309230 Z44095 XM_006717316 XP_006717379 XR_929874 NM_001005373 NP_001005373 NM_001005374 NP_001005374 NM_001190723 NP_001177652 NM_138361 NP_612370
Function	E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. {ECO:0000269|PubMed:15256501}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15256501}. Note=Displays a punctuate distribution and localizes to a submembranal ring.
Tissue Specificity	Highly expressed in adult spinal cord motoneurons as well as in fetal spinal cord and muscle tissue. {ECO:0000269|PubMed:22012984}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LRSAM1 CRISPR/Cas9 KO Plasmid (h) - sc-407099 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LRSAM1 HDR Plasmid (h) - sc-407099-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LRSAM1 Double Nickase Plasmid (h) - sc-407099-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LRSAM1 Double Nickase Plasmid (h2) - sc-407099-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LRSAM1 CRISPR Activation Plasmid (h) - sc-407099-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LRSAM1 CRISPR Activation Plasmid (h2) - sc-407099-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LRSAM1 Lentiviral Activation Particles (h) - sc-407099-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LRSAM1 Lentiviral Activation Particles (h2) - sc-407099-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LRSAM1 siRNA (h) - sc-92826 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LRSAM1 shRNA Plasmid (h) - sc-92826-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LRSAM1 shRNA (h) Lentiviral Particles - sc-92826-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LRSAM1 RNAi - H00090678-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

LRSAM1 RNAi - H00090678-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU083491 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12785 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12785 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04336 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr04336

LRSAM1 siRNA (Human) - CRJ3977 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

LRSAM1 RNAi - H00090678-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

LRSAM1 CRISPR/Cas9 KO Plasmid (h2) - sc-407099-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LRSAM1 HDR Plasmid (h2) - sc-407099-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human LRSAM1 (NM_138361.5) - SHH335123 from Creative biogene Category siRNA Species Reactivities Human

LRSAM1 shRNA Plasmid (Human) - CHJ3977 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

LRSAM1 miRNA 3'UTR clone - MiUTR3H-11561 from Creative biogene Species Reactivities Human

LRSAM1 miRNA 3'UTR clone - MiUTR3H-11562 from Creative biogene Species Reactivities Human

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