Gene Symbol | LRSAM1 |
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Entrez Gene | 90678 |
Alt Symbol | CMT2P, RIFLE, TAL |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat and sterile alpha motif containing 1 |
Other Description | E3 ubiquitin-protein ligase LRSAM1|Tsg101-associated ligase |
Swissprots | Q6UWE0 Q5VVV0 Q96MZ7 Q96GT5 Q96MX5 Q8NB40 |
Accessions | EAW87671 EAW87672 EAW87673 EAW87674 Q6UWE0 AF086398 AI364608 AK056203 BAB71119 AK056305 BAB71144 AK091589 BAC03703 AK097094 AK226106 AY358830 AAQ89189 BC009239 AAH09239 DA165729 DA393757 DA726792 DB165274 DB309230 Z44095 XM_006717316 XP_006717379 XR_929874 NM_001005373 NP_001005373 NM_001005374 NP_001005374 NM_001190723 NP_001177652 NM_138361 NP_612370 |
Function | E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. {ECO:0000269|PubMed:15256501}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15256501}. Note=Displays a punctuate distribution and localizes to a submembranal ring. |
Tissue Specificity | Highly expressed in adult spinal cord motoneurons as well as in fetal spinal cord and muscle tissue. {ECO:0000269|PubMed:22012984}. |
Human LRSAM1 full length protein - ab132832 from Abcam
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LRSAM1 Antibody Blocking Peptide - LS-E2083 from LifeSpan Bioscience
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Recombinant Human LRSAM1 Protein - H00090678-P01 from Novus Biologicals
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LRSAM1-Antibody-N-term-Blocking-peptide - BP12973a from Abgent, a WuXi AppTec company
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LRSAM1 - H00090678-P01-10 from Acris Antibodies
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LRSAM1 - H00090678-P01-25 from Acris Antibodies
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LRSAM1 fusion protein - ag20415 from Proteintech Group
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Recombinant Human LRSAM1, His-tagged - LRSAM1-29433TH from Creative Biomart
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Recombinant Human E3 ubiquitin-protein ligase LRSAM1(LRSAM1) - CSB-YP751010HU CSB-EP751010HU CSB-BP751010HU CSB-MP751010HU from Cusabio
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LRSAM1 (transcript variant 2) - TP300920 from Acris Antibodies
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LRSAM1 (transcript variant 1) - TP315025 from Acris Antibodies
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LRSAM1 (transcript variant 3) - TP323778 from Acris Antibodies
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LRSAM1 Recombinant Protein Antigen - NBP1-82017PEP from Novus Biologicals
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LRSAM1 Recombinant Protein Antigen - NBP1-82016PEP from Novus Biologicals
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LRSAM1 Peptide, Human - M34GP08952H from Creative Peptides
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E3 ubiquitin-protein ligase LRSAM1 (LRSAM1), Recombinant Protein - MBS1327712 from MyBioSource
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