SHC3

Gene Symbol	SHC3
Entrez Gene	53358
Alt Symbol	N-Shc, NSHC, RAI, SHCC
Species	Human
Gene Type	protein-coding
Description	SHC (Src homology 2 domain containing) transforming protein 3
Other Description	SH2 domain protein C3|SHC-transforming protein 3|SHC-transforming protein C|neuronal Shc|protein Rai|src homology 2 domain-containing transforming protein C3|src homology 2 domain-containing-transforming protein C3
Swissprots	Q8TAP2 Q5T7I7 Q92529 Q9UCX5
Accessions	EAW62759 EAW62760 Q92529 AK127258 BC026314 AAH26314 BC042431 BX538228 BX641139 D84361 BAA12322 DQ896663 ABM87662 HG502215 HG502216 HG502217 XM_011518785 XP_011517087 XM_011518786 XP_011517088 NM_016848 NP_058544
Function	Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Tissue Specificity	Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord. {ECO:0000269|PubMed:8808684}.
Top Pathways	Neurotrophin signaling pathway, Prolactin signaling pathway, Alcoholism, Estrogen signaling pathway, Bacterial invasion of epithelial cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SHC3 full length protein - ab162689 from Abcam Category Protein Source Wheat germ Species Human

Human SHC3 protein fragment - ab162690 from Abcam Category Protein Source Wheat germ Species Human

SHC3 / SHCC Antibody Blocking Peptide - LS-E20755 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SHC3 / SHCC Antibody Blocking Peptide - LS-E20754 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SHC3 Protein - H00053358-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SHC3 Protein - H00053358-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SHC3-Antibody-C-term-E503-Blocking-Peptide - BP8615b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Shc3 Blocking Peptide - 33R-7355 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SHC3 Blocking Peptide - 33R-8036 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SHC3 / NSHC - H00053358-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SHC3 / NSHC - H00053358-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SHC3 / NSHC - H00053358-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SHC3 / NSHC - H00053358-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SHC3 fusion protein - Ag3115 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SHC3, GST-tagged - SHC3-2655H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant SHC-Transforming Protein 3 (SHC3) - RPE670Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant SHC-Transforming Protein 3 (SHC3) - RPE670Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human SHC-transforming protein 3(SHC3) - CSB-YP838779HU CSB-EP838779HU CSB-BP838779HU CSB-MP838779HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SHC3 Recombinant Protein Antigen - NBP2-13307PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SHC3 Peptide, Human - M34GP14199H from Creative Peptides Category Peptide Source Synthetic. Species Human

SHC3 Recombinant Protein (OPCD06958) - OPCD06958 from Aviva Systems Biology Category Protein Source E.coli Species Human

SHC3 Recombinant Protein Antigen - NBP2-56058PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SHC-transforming protein 3 (SHC3), Recombinant Protein - MBS1359508 from MyBioSource Category Protein Prices $1,395.00, $1,395.00, $1,615.00, $1,615.00, $2,330.00, $2,330.00, $2,775.00, $2,775.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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