SHC3

Gene Symbol SHC3
Entrez Gene 53358
Alt Symbol N-Shc, NSHC, RAI, SHCC
Species Human
Gene Type protein-coding
Description SHC (Src homology 2 domain containing) transforming protein 3
Other Description SH2 domain protein C3|SHC-transforming protein 3|SHC-transforming protein C|neuronal Shc|protein Rai|src homology 2 domain-containing transforming protein C3|src homology 2 domain-containing-transforming protein C3
Swissprots Q8TAP2 Q5T7I7 Q92529 Q9UCX5
Accessions EAW62759 EAW62760 Q92529 AK127258 BC026314 AAH26314 BC042431 BX538228 BX641139 D84361 BAA12322 DQ896663 ABM87662 HG502215 HG502216 HG502217 XM_011518785 XP_011517087 XM_011518786 XP_011517088 NM_016848 NP_058544
Function Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Tissue Specificity Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord. {ECO:0000269|PubMed:8808684}.
Top Pathways Neurotrophin signaling pathway, Prolactin signaling pathway, Alcoholism, Estrogen signaling pathway, Bacterial invasion of epithelial cells

N-Shc CRISPR/Cas9 KO Plasmid (h) - sc-401571 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-Shc HDR Plasmid (h) - sc-401571-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-Shc Double Nickase Plasmid (h) - sc-401571-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-Shc Double Nickase Plasmid (h2) - sc-401571-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-Shc CRISPR Activation Plasmid (h) - sc-401571-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-Shc CRISPR Activation Plasmid (h2) - sc-401571-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-Shc Lentiviral Activation Particles (h) - sc-401571-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-Shc Lentiviral Activation Particles (h2) - sc-401571-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-Shc siRNA (h) - sc-40975 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

N-Shc shRNA Plasmid (h) - sc-40975-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

N-Shc shRNA (h) Lentiviral Particles - sc-40975-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU027781 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19292 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19292 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02847 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02847

SHC3 siRNA (Human) - CRH9969 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SHC3 - MBS8229468 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SHC3 (NM_016848.5) - SHH406988 from Creative biogene

Category siRNA
Species Reactivities Human

Human SHC3 siRNA - orb270471 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SHC3 shRNA Plasmid (Human) - CHH9969 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SHC3 miRNA 3'UTR clone - MiUTR1H-09377 from Creative biogene

Species Reactivities Human
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