Gene Symbol | PRSS3 |
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Entrez Gene | 5646 |
Alt Symbol | MTG, PRSS4, T9, TRY3, TRY4 |
Species | Human |
Gene Type | protein-coding |
Description | protease, serine, 3 |
Other Description | brain trypsinogen|mesotrypsin|mesotrypsinogen|pancreatic trypsinogen III|protease, serine, 4 (trypsin 4, brain)|trypsin III|trypsin IV|trypsin-3|trypsinogen 4|trypsinogen 5|trypsinogen IV |
Swissprots | A8CED1 E7ES07 Q5VXV0 P15951 P35030 Q9UQV3 F8W7P3 Q6ISJ4 A8CED3 Q15665 A9Z1Y4 |
Accessions | AAC13322 EAW58481 EAW58482 EAW58483 EAW58484 P35030 AB298285 BAF80324 AB298286 BAF80325 AY052783 AAL14243 BC030238 AAH30238 BC069476 AAH69476 BC069494 AAH69494 D45417 BAA08257 HQ448195 ADQ32676 X15505 CAA33527 X71345 CAA50484 X72781 CAB58178 XM_011517965 XP_011516267 NM_001197097 NP_001184026 NM_001197098 NP_001184027 NM_002771 NP_002762 NM_007343 NP_031369 |
Function | Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5. {ECO:0000269|PubMed:12021776, ECO:0000269|PubMed:14507909}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in pancreas and brain. Also expressed in Paneth cells, at the base of small intestinal crypts. {ECO:0000269|PubMed:12021776}. |
Top Pathways | Protein digestion and absorption, Pancreatic secretion, Influenza A, Neuroactive ligand-receptor interaction |
Anti-PRSS3 antibody - ab170361 from Abcam
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Anti-PRSS3 antibody - ab107430 from Abcam
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Anti-PRSS3 antibody - ab201207 from Abcam
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Anti-PRSS3 antibody - ab135869 from Abcam
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Anti-PRSS3 antibody - ab105123 from Abcam
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Anti-PRSS3 antibody (Biotin) - ab193994 from Abcam
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Anti-PRSS3 / Trypsin 3 Antibody (aa16-246) - LS-C39954 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody - LS-C83038 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody - LS-C83039 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody - LS-C83041 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody - LS-C132707 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody (aa143-171, APC) - LS-C284800 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody (aa143-171, AP) - LS-C284801 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody (aa143-171, PE) - LS-C284802 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody (aa20-48, AP) - LS-C284803 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody (aa20-48, APC) - LS-C284804 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody (aa20-48, PE) - LS-C284805 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody (HRP) - LS-C316595 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody - LS-C211416 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody (HRP) - LS-C211420 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody (FITC) - LS-C316596 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody - LS-C318695 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody (Met166) - LS-C177742 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody (Biotin) - LS-C316598 from LifeSpan Bioscience
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Anti-PRSS3 / Trypsin 3 Antibody (aa143-171) - LS-C324335 from LifeSpan Bioscience
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