Gene Symbol | PRSS3 |
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Entrez Gene | 5646 |
Alt Symbol | MTG, PRSS4, T9, TRY3, TRY4 |
Species | Human |
Gene Type | protein-coding |
Description | protease, serine, 3 |
Other Description | brain trypsinogen|mesotrypsin|mesotrypsinogen|pancreatic trypsinogen III|protease, serine, 4 (trypsin 4, brain)|trypsin III|trypsin IV|trypsin-3|trypsinogen 4|trypsinogen 5|trypsinogen IV |
Swissprots | A8CED1 E7ES07 Q5VXV0 P15951 P35030 Q9UQV3 F8W7P3 Q6ISJ4 A8CED3 Q15665 A9Z1Y4 |
Accessions | AAC13322 EAW58481 EAW58482 EAW58483 EAW58484 P35030 AB298285 BAF80324 AB298286 BAF80325 AY052783 AAL14243 BC030238 AAH30238 BC069476 AAH69476 BC069494 AAH69494 D45417 BAA08257 HQ448195 ADQ32676 X15505 CAA33527 X71345 CAA50484 X72781 CAB58178 XM_011517965 XP_011516267 NM_001197097 NP_001184026 NM_001197098 NP_001184027 NM_002771 NP_002762 NM_007343 NP_031369 |
Function | Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5. {ECO:0000269|PubMed:12021776, ECO:0000269|PubMed:14507909}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in pancreas and brain. Also expressed in Paneth cells, at the base of small intestinal crypts. {ECO:0000269|PubMed:12021776}. |
Top Pathways | Protein digestion and absorption, Pancreatic secretion, Influenza A, Neuroactive ligand-receptor interaction |
Human PRSS3 full length protein - ab159245 from Abcam
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Human PRSS3 full length protein - ab167856 from Abcam
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Human PRSS3 full length protein - ab185590 from Abcam
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PRSS3 / Trypsin 3 Antibody Blocking Peptide - LS-E1308 from LifeSpan Bioscience
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PRSS3 / Trypsin 3 Antibody Blocking Peptide - LS-E252 from LifeSpan Bioscience
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PRSS3 / Trypsin 3 Antibody Blocking Peptide - LS-E20493 from LifeSpan Bioscience
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Recombinant Human Trypsin 3/PRSS3 Protein - NBP2-23371 from Novus Biologicals
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Trypsin 3/PRSS3 Recombinant Protein - H00005646-P01 from Novus Biologicals
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PRSS3-Antibody-N-term-Blocking-Peptide - BP10489a from Abgent, a WuXi AppTec company
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PRSS3-Antibody-Center-Blocking-peptide - BP11927c from Abgent, a WuXi AppTec company
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Recombinant Human Active Trypsin 3/PRSS3, CF - 3714-SE-010 from R&D Systems
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Recombinant Human Trypsin 3/PRSS3, CF - 3710-SE-010 from R&D Systems
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Recombinant human Trypsin-3 (OPCA00960) - OPCA00960 from Aviva Systems Biology
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Human Brain trypsinogen protein - orb84187 from Biorbyt
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Human PRSS3 Enzyme - orb191442 from Biorbyt
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PRSS3 Blocking Peptide - 33R-9443 from Fitzgerald
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PRSS3 protein (His tag) - 80R-2961 from Fitzgerald
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TRP3 protein - 30R-3230 from Fitzgerald
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Trypsin protein - 30-AT45-L from Fitzgerald
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Trypsin protein - 30-AT45 from Fitzgerald
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Trypsin-3 / PRSS3 (81-304, His-tag) - AR51079PU-N from Acris Antibodies
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Trypsin-3 / PRSS3 (81-304, His-tag) - AR51079PU-S from Acris Antibodies
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Trypsin-3 / PRSS3 - H00005646-P01-10 from Acris Antibodies
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Trypsin-3 / PRSS3 - H00005646-P01-25 from Acris Antibodies
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PRSS3, 81-304aa, Human, His tag, E.coli - 01-P2255 from ARP American Research Products
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