IL1A

Gene Symbol IL1A
Entrez Gene 3552
Alt Symbol IL-1A, IL1, IL1-ALPHA, IL1F1
Species Human
Gene Type protein-coding
Description interleukin 1, alpha
Other Description IL-1 alpha|hematopoietin-1|interleukin-1 alpha|preinterleukin 1 alpha|pro-interleukin-1-alpha
Swissprots Q7RU02 Q53QF9 P01583
Accessions AAM96189 AAX93054 CAA27448 CAD29871 EAW73604 P01583 AK314850 BAG37367 BC013142 AAH13142 BC035169 BT007014 AAP35660 CA307202 CR457414 CAG33695 DQ890675 ABM81601 DQ893856 ABM84782 M15329 AAA59133 X02531 CAA26371 X02851 CAA26604 X56086 CAA39566 NM_000575 NP_000566
Function Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Subcellular Location Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
Top Pathways Tuberculosis, Measles, Influenza A, Salmonella infection, Inflammatory bowel disease (IBD)

IL-1α CRISPR/Cas9 KO Plasmid (h) - sc-418057 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1α HDR Plasmid (h) - sc-418057-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1α Double Nickase Plasmid (h) - sc-418057-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1α Double Nickase Plasmid (h2) - sc-418057-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1α CRISPR Activation Plasmid (h) - sc-418057-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1α CRISPR Activation Plasmid (h2) - sc-418057-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1α Lentiviral Activation Particles (h) - sc-418057-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1α Lentiviral Activation Particles (h2) - sc-418057-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1α siRNA (h) - sc-39613 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-1α shRNA Plasmid (h) - sc-39613-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-1α shRNA (h) Lentiviral Particles - sc-39613-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-1 alpha/IL-1F1 RNAi - H00003552-R01 from Novus Biologicals

Category siRNA
Prices $339.00, $399.00
Sizes 10 nmol, 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU150811 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1750 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1750 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

IL1A siRNA (Human) - CRH2371 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IL1A - MBS8214022 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IL1A (NM_000575.3) - SHH318477 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human IL1A(NM_000575.3) - SHL172092 from Creative biogene

Category siRNA
Species Reactivities Human

IL1A shRNA Plasmid (Human) - CHH2371 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IL1A miRNA 3'UTR clone - MiUTR1H-04887 from Creative biogene

Species Reactivities Human
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