Gene Symbol | IL1A |
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Entrez Gene | 3552 |
Alt Symbol | IL-1A, IL1, IL1-ALPHA, IL1F1 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 1, alpha |
Other Description | IL-1 alpha|hematopoietin-1|interleukin-1 alpha|preinterleukin 1 alpha|pro-interleukin-1-alpha |
Swissprots | Q7RU02 Q53QF9 P01583 |
Accessions | AAM96189 AAX93054 CAA27448 CAD29871 EAW73604 P01583 AK314850 BAG37367 BC013142 AAH13142 BC035169 BT007014 AAP35660 CA307202 CR457414 CAG33695 DQ890675 ABM81601 DQ893856 ABM84782 M15329 AAA59133 X02531 CAA26371 X02851 CAA26604 X56086 CAA39566 NM_000575 NP_000566 |
Function | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
Subcellular Location | Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
Top Pathways | Tuberculosis, Measles, Influenza A, Salmonella infection, Inflammatory bowel disease (IBD) |
Active human IL1 alpha full length protein - ab119165 from Abcam
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Active human IL1 alpha full length protein - ab174089 from Abcam
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Active human IL1 alpha full length protein - ab9615 from Abcam
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Active human IL1 alpha full length protein - ab192121 from Abcam
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Active human IL1 alpha full length protein - ab73567 from Abcam
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Active mouse IL1 alpha full length protein - ab151821 from Abcam
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Active mouse IL1 alpha full length protein - ab119727 from Abcam
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Active mouse IL1 alpha full length protein - ab9725 from Abcam
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Active mouse IL1 alpha protein fragment - ab200282 from Abcam
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Active mouse IL1 alpha protein fragment - ab73570 from Abcam
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Active pig IL1 alpha protein fragment - ab73573 from Abcam
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Active rat IL1 alpha full length protein - ab9877 from Abcam
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Active rat IL1 alpha protein fragment - ab200276 from Abcam
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Active rat IL1 alpha protein fragment - ab73572 from Abcam
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Bottlenose Dolphin IL1 alpha protein fragment - ab117469 from Abcam
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Cow IL1 alpha protein fragment - ab87390 from Abcam
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Dog IL1 alpha full length protein - ab169717 from Abcam
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Human IL1 alpha full length protein - ab53665 from Abcam
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Human IL1 alpha full length protein - ab194165 from Abcam
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Human IL1 alpha protein fragment - ab73569 from Abcam
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Rabbit IL1 alpha full length protein - ab128525 from Abcam
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IL1A / IL-1 Alpha Antibody Blocking Peptide - LS-E19543 from LifeSpan Bioscience
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IL1A / IL-1 Alpha Antibody Blocking Peptide - LS-E8508 from LifeSpan Bioscience
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IL1A / IL-1 Alpha Antibody Blocking Peptide - LS-E8509 from LifeSpan Bioscience
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Recombinant Human IL-1 alpha/IL-1F1 Protein - NBP2-35051 from Novus Biologicals
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