IL1A

Gene Symbol IL1A
Entrez Gene 3552
Alt Symbol IL-1A, IL1, IL1-ALPHA, IL1F1
Species Human
Gene Type protein-coding
Description interleukin 1, alpha
Other Description IL-1 alpha|hematopoietin-1|interleukin-1 alpha|preinterleukin 1 alpha|pro-interleukin-1-alpha
Swissprots Q7RU02 Q53QF9 P01583
Accessions AAM96189 AAX93054 CAA27448 CAD29871 EAW73604 P01583 AK314850 BAG37367 BC013142 AAH13142 BC035169 BT007014 AAP35660 CA307202 CR457414 CAG33695 DQ890675 ABM81601 DQ893856 ABM84782 M15329 AAA59133 X02531 CAA26371 X02851 CAA26604 X56086 CAA39566 NM_000575 NP_000566
Function Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Subcellular Location Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
Top Pathways Tuberculosis, Measles, Influenza A, Salmonella infection, Inflammatory bowel disease (IBD)

IL-1α (3564/3B3-14) - sc-73494 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IL-1α (3564/3B3-14): sc-73494. Western blot analysis of IL-1α expression in HeLa whole cell lysate.

IL-1α (G-10) - sc-271618 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IL-1α (G-10): sc-271618. Western blot analysis of IL-1α expression in non-transfected: sc-110760 (A) and human IL-1α transfected: sc-111172 (B) 293 whole cell lysates.

IL-1α (5G3) - sc-130325 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IL-1α (5G3): sc-130325. Western blot analysis of human recombinant IL-1α.

IL-1α (ALF-161) - sc-12741 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Hamster
Clonality Monoclonal
IL-1α (ALF-161): sc-12741. Western blot analysis of mouse recombinant IL-1α.

IL-1α (B-7) - sc-9983 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IL-1α (B-7): sc-9983. Immunoperoxidase staining of formalin fixed, paraffin-embedded human endometrium tissue showing cytoplasmic staining of glandular cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

IL-1α (3B3) - sc-53350 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

IL-1α (H-159) - sc-7929 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of human recombinant IL-1α. Antibodies tested include IL-1α (H-159): sc-7929 (A) and IL-1α (B-7): sc-9983 (B).

IL-1α (1F3B3) - sc-32814 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IL-1α (1F3B3): sc-32814. Western blot analysis of human recombinant IL-1α.

Anti-IL1 alpha antibody - ab7632 from Abcam

Prices $385.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal
ab7632 staining IL1 alpha in murine RAW 264.7 cells by Immunocytochemistry/ Immunofluorescence.Cells were fixed in paraformaldehyde, permeabilized using 0.1% Triton-X100 in 2% BSA for 15 minutes, blocked with 2% BSA for 1 hour at 4°C and then incubated with ab7632 at a 1/100 dilution for 16 hours at 4°C. The secondary used was an Alexa-Fluor 488 conjugated chicken anti-rabbit IgG (H+L) used at a 1/500 dilution.See Abreview

Anti-IL1 alpha antibody - ab9614 from Abcam

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab9614 at 1.0 µg/ml staining normal human skin by IHC-P. The antibody was incubated overnight at 4°C. An HRP-labeled polymer detection system was used with a non-alcohol soluble AEC chromogen. Enzyme induced antigen retrieval was performed with proteinase K.

Anti-IL1 alpha antibody - ab92396 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IL1 alpha antibody (ab92396) at 1/100 dilutionLane 1 : Non-transfected 293 cell lysateLane 2 : IL1 alpha transfected 293 cell lysateLysates/proteins at 2 µg per lane.

Anti-IL1 alpha antibody - ab14306 from Abcam

Prices $376.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Anti-IL1 alpha antibody (ab14306) at 1/2000 dilution + E.coli derived IL1 alpha fusion protein.SecondaryHRP conjugated goat anti IgY at 1/1000 dilution

Anti-IL1 alpha antibody - ab157746 from Abcam

Host Sheep
Clonality Polyclonal

Anti-IL1 alpha antibody [5G3] - ab67456 from Abcam

Prices $378.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5G3
Anti-IL1 alpha antibody [5G3] (ab67456) + recombinant IL1 alpha

Anti-IL1 alpha antibody [AS5] - ab17281 from Abcam

Prices $378.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone AS5
ab17281 staining IL1 alpah in human colon tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Tissue was fixed with paraformaldehyde and a heat mediated antigen retrieval step was performed using EDTA buffer pH 9.0. Samples were then blocked with 10% serum for 30 minutes at 21°C followed by incubation with the primary antibody at a 1/200 dilution for 30 minutes at 21°C. A undiluted HRP-conjugated goat polyclonal was used as secondary antibody.See Abreview

Anti-IL1 alpha antibody [AS6] (Biotin) - ab16163 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone AS6

Anti-IL1 alpha antibody [EPR5103(2)] - ab134908 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5103(2)
Anti-IL1 alpha antibody [EPR5103(2)] (ab134908) at 1/1000 dilution + Human skin tissue lysate at 10 µgSecondaryHRP-conjugated goat anti-rabbit IgG polyclonal at 1/2000 dilution

Anti-IL1A Antibody (clone 1G2) - LS-C338216 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1G2
Immunofluorescent staining of HeLa cells using anti-IL1A mouse monoclonal antibody.

Anti-IL1A / IL-1 Alpha Antibody (clone 2F11) - LS-C338217 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F11
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-IL1A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-IL1A / IL-1 Alpha Antibody (clone 2F8) - LS-C338218 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F8
IHC of paraffin-embedded Human lymph node tissue using anti-IL1A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-IL1A / IL-1 Alpha Antibody - LS-C104666 from LifeSpan Bioscience

Prices $285.00, $325.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal
IHC of IL1A / IL1 Alpha antibody LS-C104666

Anti-IL1A / IL-1 Alpha Antibody - LS-C7666 from LifeSpan Bioscience

Prices $575.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal

Anti-IL1A / IL-1 Alpha Antibody - LS-C7663 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IL1A Antibody - LS-C7665 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-IL1A / IL-1 Alpha Antibody - LS-C7678 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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