Fgfr1

Gene Symbol	Fgfr1
Entrez Gene	14182
Alt Symbol	AW208770, Eask, FLG, Fgfr-1, Flt-2, Hspy, MFR, bFGF-R-1, c-fgr
Species	Mouse
Gene Type	protein-coding
Description	fibroblast growth factor receptor 1
Other Description	basic fibroblast growth factor receptor 1|proto-oncogene c-Fgr
Swissprots	Q9QZM7 Q60830 Q61562 Q01736 Q8CFK8 E9Q2P4 P16092 Q80T10
Accessions	AAD38071 AAF82386 EDL32833 EDL32834 EDL32835 EDL32836 P16092 AF176552 AAF05312 AI480534 AK028354 BAC25899 AK034295 BAC28662 AK049704 AK086091 AK167639 BAE39690 BC010200 AAH10200 BC033447 AAH33447 BC053921 BU611199 CB524826 CF532036 M28998 AAA37290 M33760 AAA37622 M65053 AAA37620 S47233 S74765 AAB32844 U22324 AAC52182 U23445 AAC52183 X51893 CAA36175 X57790 CAA40932 XM_006509010 XP_006509073 XM_006509012 XP_006509075 XM_006509013 XP_006509076 XM_011242120 XP_011240422 XM_011242121 XP_011240423 XM_011242122 XP_011240424 XM_011242123 XP_011240425 NM_001079908 NP_001073377 NM_001079909 NP_001073378 NM_010206 NP_034336
Function	Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to
Subcellular Location	Isoform 5: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:10821861}.
Top Pathways	Adherens junction, PI3K-Akt signaling pathway, MAPK signaling pathway, Signaling pathways regulating pluripotency of stem cells, Prostate cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Basic fibroblast growth factor receptor 1 (FGFR1), Mouse, ELISA Kit - E03B0911 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Fibroblast Growth Factor Receptor 1 (FGFR1), Mouse, ELISA Kit - SEB791Mu from ARP American Research Products Category ELISA Kit Prices $704.00 Sizes 96 t Sensitivity 0.061ng/mL Range 0.156-10ng/mL

Fibroblast growth factor receptor 1, Fgfr1, Mouse, ELISA Kit - E0074m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Filaggrin (FLG), Mouse, ELISA Kit - CSB-EL008712MO from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.78 pg/ml Range 3.12 pg/ml-200 pg/ml

Filaggrin, Flg, Mouse, ELISA Kit - E1186m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Tyrosine-protein kinase Fgr (FGR), Mouse, ELISA Kit - CSB-EL008655MO from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Basic fibroblast growth factor receptor 1 (FGFR1), ELISA Kit - MBS7251940 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibroblast Growth Factor Receptor 1, ELISA Kit - MBS084408 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Fibroblast Growth Factor Receptor 1 (FGFR1) - SEB791Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.061ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Mouse Fibroblast Growth Factor Receptor 1 (FGFR1) ELISA Kit - EKU04189 from Biomatik Category ELISA Kit Prices $718.00, $3,196.00, $5,817.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.061 ng/mL Range 0.156-10 ng/mL

Mouse FGFR1(Fibroblast Growth Factor Receptor 1) ELISA Kit - E-EL-M2416 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.1 ng/mL Range 0.16~10 ng/mL

Mouse FGFR1 ELISA Kit - abx154015 from Abbexa Category ELISA Kit Sensitivity 0.061 ng/ml Range 0.156 ng/ml - 10 ng/ml

Fibroblast Growth Factor Receptor 1 (FGFR1), Mouse, ELISA Kit - DL-FGFR1-Mu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Range 0.156-10 ng/mL

Filaggrin (FLG), Mouse, ELISA Kit - DL-FLG-Mu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Range 0.156-10 ng/mL

Mouse FGFR1(Fibroblast Growth Factor Receptor 1) ELISA Kit - E-EL-M2416 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Fibroblast Growth Factor Receptor 1, FGFR1, Mouse, ELISA Kit - E-EL-M2416 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Mouse FGFR1 ELISA Kit - abx570528 from Abbexa Category ELISA Kit Sensitivity 0.061 ng/ml Range 0.156 ng/ml - 10 ng/ml

Mouse FLG ELISA Kit - abx573034 from Abbexa Category ELISA Kit Sensitivity 0.136 ng/ml Range 0.313 ng/ml - 20 ng/ml

Mouse Fgfr1 ELISA Kit - E045486 from Biobool Category ELISA Kit

Mouse Flg ELISA Kit - E053166 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of mouse FLG is typically less than 0.78 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean

FGFR1 ELISA Kit (Mouse) (OKCD02555) - OKCD02555 from Aviva Systems Biology Category ELISA Kit Prices $535.00 Sizes 10 ng Sensitivity 0.061 ng/mL Range 0.156-10 ng/mL

FLG ELISA Kit (Mouse) (OKCD02558) - OKCD02558 from Aviva Systems Biology Category ELISA Kit Prices $555.00 Sizes 20 ng Sensitivity 0.114 ng/mL Range 0.312-20 ng/mL

Fibroblast growth factor receptor 1, ELISA Kit - MBS289280 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibroblast Growth Factor Receptor 1 (FGFR1), ELISA Kit - MBS451626 from MyBioSource Category ELISA Kit Prices $365.00, $485.00, $2,095.00, $4,065.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.061ng/mL Range 0.156-10ng/mL

FLG ELISA Kit (Mouse) (OKEH06971) - OKEH06971 from Aviva Systems Biology Category ELISA Kit Sensitivity 0.625 ng/mL Range 0.625 - 40 ng/mL

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