Fgfr1

Gene Symbol Fgfr1
Entrez Gene 14182
Alt Symbol AW208770, Eask, FLG, Fgfr-1, Flt-2, Hspy, MFR, bFGF-R-1, c-fgr
Species Mouse
Gene Type protein-coding
Description fibroblast growth factor receptor 1
Other Description basic fibroblast growth factor receptor 1|proto-oncogene c-Fgr
Swissprots Q9QZM7 Q60830 Q61562 Q01736 Q8CFK8 E9Q2P4 P16092 Q80T10
Accessions AAD38071 AAF82386 EDL32833 EDL32834 EDL32835 EDL32836 P16092 AF176552 AAF05312 AI480534 AK028354 BAC25899 AK034295 BAC28662 AK049704 AK086091 AK167639 BAE39690 BC010200 AAH10200 BC033447 AAH33447 BC053921 BU611199 CB524826 CF532036 M28998 AAA37290 M33760 AAA37622 M65053 AAA37620 S47233 S74765 AAB32844 U22324 AAC52182 U23445 AAC52183 X51893 CAA36175 X57790 CAA40932 XM_006509010 XP_006509073 XM_006509012 XP_006509075 XM_006509013 XP_006509076 XM_011242120 XP_011240422 XM_011242121 XP_011240423 XM_011242122 XP_011240424 XM_011242123 XP_011240425 NM_001079908 NP_001073377 NM_001079909 NP_001073378 NM_010206 NP_034336
Function Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to
Subcellular Location Isoform 5: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:10821861}.
Top Pathways Adherens junction, PI3K-Akt signaling pathway, MAPK signaling pathway, Signaling pathways regulating pluripotency of stem cells, Prostate cancer

Mouse-Fgfr1-Antibody-C-term-Blocking-Peptide - BP14840b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg
Species Mouse

Mouse Fibroblast Growth Factor Receptor 1 protein - orb84051 from Biorbyt

Category Protein
Prices $434.00, $646.00
Sizes 50 μg, 100 μg
Source Human
Species Mouse
SDS-PAGE analysis of mouse FGFR1 Fc tag protein

Mouse Fibroblast Growth Factor Receptor 1 protein - orb84050 from Biorbyt

Category Protein
Prices $570.00, $859.00
Sizes 50 μg, 100 μg
Source Human
Species Mouse
SDS-PAGE analysis of mouse FGFR1 His tag protein

Recombinant Mouse Fgfr1, Fc tagged - Fgfr1-4015M from Creative Biomart

Category Protein
Source Human Cells
Species Mouse

Recombinant Mouse Fgfr1, His tagged - Fgfr1-4016M from Creative Biomart

Category Protein
Source Human Cells
Species Mouse

FGFR1 / CD331 - PN201619 from Elabscience

Category Protein
Prices $225.00, $475.00
Sizes 10 μg, 50 μg
Source Human Cells
Species Mouse

Mouse FGFR1 / CD331 Protein (His Tag) - 50186-M08H-50 from Sino Biological

Category Protein
Source Human Cells
Species Mouse

Mouse FGFR1 / CD331 Protein (Fc Tag) - 50186-M02H-50 from Sino Biological

Category Protein
Source Human Cells
Species Mouse

Recombinant Fibroblast Growth Factor Receptor 1 (FGFR1) - RPB791Mu01 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Fibroblast Growth Factor Receptor 1 (FGFR1) - RPB791Mu02 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse Fibroblast growth factor receptor 1(Fgfr1) - CSB-YP008642MO CSB-EP008642MO CSB-BP008642MO CSB-MP008642MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Recombinant Mouse FGFR1 / CD331 Protein (His tag) - PKSM040821 from Elabscience

Category Protein
Source Human Cells
Species Mouse

Recombinant Mouse FGFR1 / CD331 Protein (Fc tag)(Fc tag) - PKSM040822 from Elabscience

Category Protein
Source Human Cell
Species Mouse

Fibroblast growth factor receptor 1 (Fgfr1), Recombinant Protein - MBS953115 from MyBioSource

Category Protein
Prices $1,120.00, $1,120.00, $1,350.00, $1,350.00, $1,775.00, $1,775.00, $2,240.00, $2,240.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

Mouse FGFR1 / CD331 Protein (Fc Tag) - 50186-M02H from ABclonal

Category Protein
Prices $198.00, $348.00
Sizes 50 µg, 100 µg
Source Human Cells
Species Mouse

Mouse FGFR1 / CD331 Protein (His Tag) - 50186-M08H from ABclonal

Category Protein
Prices $198.00, $348.00
Sizes 50 µg, 100 µg
Source Human Cells
Species Mouse

FGFR1 / CD331, Recombinant Protein - MBS2547119 from MyBioSource

Category Protein
Prices $525.00, $905.00
Sizes 50 µg, 100 µg
Source Human Cells

FGFR1 / CD331, Recombinant Protein - MBS2547120 from MyBioSource

Category Protein
Prices $525.00, $905.00
Sizes 50 µg, 100 µg
Source Human Cells
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