IL23R

Gene Symbol	IL23R
Entrez Gene	149233
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	interleukin 23 receptor
Other Description	IL-23 receptor|interleukin-23 receptor
Swissprots	Q4VGP6 Q4VGP5 Q4VGP1 Q4VGP3 Q5VWK7 C9JGX4 Q96AS1 Q4VGP2 Q8IW84 Q8NFQ9 Q5VWK5 Q4VGP4
Accessions	BAJ13471 EAX06501 EAX06502 Q5VWK5 AF461422 AAM44229 AM990313 CAQ51232 AM990314 CAQ51233 AM990315 CAQ51234 AM990316 CAQ51235 AM990317 CAQ51236 AM990318 CAQ51237 AM990319 CAQ51238 AM990320 CAQ51239 AM990321 CAQ51240 AM990322 CAQ51241 AM990323 CAQ51242 AM990324 CAQ51243 AM990325 CAQ51244 AM990326 CAQ51245 AM990327 CAQ51246 AM990328 CAQ51247 AM990329 CAQ51248 AM990330 CAQ51249 AM990331 CAQ51250 AM990332 CAQ51251 AM990333 CAQ51252 AM990334 CAQ51253 AM990335 CAQ51254 AM990336 CAQ51255 AM990337 CAQ51256 AY937250 AAY18345 AY937251 AAY18346 AY937252 AAY18347 AY937253 AAY18348 AY937254 AAY18349 AY937255 AAY18350 BC016829 AAH16829 BC040720 AAH40720 BC142955 BC166698 AAI66698 FM212237 CAR79024 FM212238 CAR79025 FM212239 CAR79026 FM212240 CAR79027 FM212241 CAR79028 XM_005270516 XP_005270573 XM_011540789 XP_011539091 XM_011540790 XP_011539092 XM_011540791 XP_011539093 NM_144701 NP_653302
Function	Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. {ECO:0000269|PubMed:12023369}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12023369}; Single-pass type I membrane protein {ECO:0000269|PubMed:12023369}.
Tissue Specificity	Expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells. {ECO:0000269|PubMed:12023369, ECO:0000269|PubMed:16372191}.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Inflammatory bowel disease (IBD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Interleukin-23 receptor Gene - orb143785 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human-IL23R-cDNA-Clone - DC07376 from Abgent, a WuXi AppTec company Prices $307.80 Sizes 10 µg Species Human Accession BC040720

IL23R - MBS1268583 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC040720

Human IL23R cDNA clone(NM_144701.2) - CDFG008652 from Creative Biomart Species Human Accession NM_144701.2

Human IL23R ORF Clone(NM_144701.2) - CDCR317770 from Creative Biomart Species Human Accession NM_144701.2

Human IL23R ORF Clone(NM_144701.2) - CDCR317771 from Creative Biomart Species Human Accession NM_144701.2

Human IL23R ORF Clone(NM_144701.2) - CDCR317772 from Creative Biomart Species Human Accession NM_144701.2

Human IL23R / IL23 Receptor Gene ORF cDNA clone in cloning vector - HG13840-G from Sino Biological Species Human

Human IL23R / IL23 Receptor Gene ORF cDNA clone expression plasmid, N-His tag - HG13840-NH from Sino Biological Species Human

Human IL23R Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG13840-G-F from Sino Biological Species Human Accession BC040720

Human IL23R Gene cDNA Clone (full-length ORF Clone), expression ready, HA-tagged - HG13840-G-Y from Sino Biological Species Human Accession BC040720

Human IL23R / IL23 Receptor Gene ORF cDNA clone expression plasmid, C-HA tag - HG13840-CY from Sino Biological Species Human

Human IL23R / IL23 Receptor Gene ORF cDNA clone expression plasmid - HG13840-UT from Sino Biological Species Human

Human IL23R / IL23 Receptor Gene ORF cDNA clone expression plasmid, C-His tag - HG13840-CH from Sino Biological Species Human

Human IL23R / IL23 Receptor Gene ORF cDNA clone expression plasmid, N-HA tag - HG13840-NY from Sino Biological Species Human

Human IL23R / IL23 Receptor Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13840-NF from Sino Biological Species Human

Human IL23R / IL23 Receptor Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13840-ACG from Sino Biological Species Human

Human IL23R / IL23 Receptor Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13840-NM from Sino Biological Species Human

Human IL23R / IL23 Receptor Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13840-CF from Sino Biological Species Human

Human IL23R / IL23 Receptor Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13840-CM from Sino Biological Species Human

Human IL23R / IL23 Receptor Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13840-ACR from Sino Biological Species Human

Mouse IL-23 R (NP_653131) VersaClone cDNA - RDC1256 from R&D Systems Prices $499.00 Sizes 10 µg Species Mouse

Human IL-23 R (AAM44229) VersaClone cDNA - RDC1255 from R&D Systems Prices $499.00 Sizes 10 µg Species Human

Human IL23R ORF clone (NM_144701.2) - CDCL120489 from Creative biogene Species Human

Human IL23R ORF Clone (BC040720) - CDCS416928 from Creative biogene Species Human Accession Q5VWK5

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