IL23R

Gene Symbol IL23R
Entrez Gene 149233
Alt Symbol -
Species Human
Gene Type protein-coding
Description interleukin 23 receptor
Other Description IL-23 receptor|interleukin-23 receptor
Swissprots Q4VGP6 Q4VGP5 Q4VGP1 Q4VGP3 Q5VWK7 C9JGX4 Q96AS1 Q4VGP2 Q8IW84 Q8NFQ9 Q5VWK5 Q4VGP4
Accessions BAJ13471 EAX06501 EAX06502 Q5VWK5 AF461422 AAM44229 AM990313 CAQ51232 AM990314 CAQ51233 AM990315 CAQ51234 AM990316 CAQ51235 AM990317 CAQ51236 AM990318 CAQ51237 AM990319 CAQ51238 AM990320 CAQ51239 AM990321 CAQ51240 AM990322 CAQ51241 AM990323 CAQ51242 AM990324 CAQ51243 AM990325 CAQ51244 AM990326 CAQ51245 AM990327 CAQ51246 AM990328 CAQ51247 AM990329 CAQ51248 AM990330 CAQ51249 AM990331 CAQ51250 AM990332 CAQ51251 AM990333 CAQ51252 AM990334 CAQ51253 AM990335 CAQ51254 AM990336 CAQ51255 AM990337 CAQ51256 AY937250 AAY18345 AY937251 AAY18346 AY937252 AAY18347 AY937253 AAY18348 AY937254 AAY18349 AY937255 AAY18350 BC016829 AAH16829 BC040720 AAH40720 BC142955 BC166698 AAI66698 FM212237 CAR79024 FM212238 CAR79025 FM212239 CAR79026 FM212240 CAR79027 FM212241 CAR79028 XM_005270516 XP_005270573 XM_011540789 XP_011539091 XM_011540790 XP_011539092 XM_011540791 XP_011539093 NM_144701 NP_653302
Function Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. {ECO:0000269|PubMed:12023369}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12023369}; Single-pass type I membrane protein {ECO:0000269|PubMed:12023369}.
Tissue Specificity Expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells. {ECO:0000269|PubMed:12023369, ECO:0000269|PubMed:16372191}.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Inflammatory bowel disease (IBD)

IL-23R (H-300) - sc-99030 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

IL-23R (C-13) - sc-47060 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IL-23R (K-13) - sc-47062 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IL-23R (N-19) - sc-47063 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-IL23 Receptor antibody - ab175072 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of MCF7 cells using ab175072. Blue DAPI for nuclear staining.

Anti-IL23 Receptor antibody - ab130661 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-IL23 Receptor antibody (ab130661) at 1/100 dilution + K562 cell lysate at 35 µg

Anti-IL23 Receptor antibody - ab58367 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-IL23 Receptor antibody - ab22059 from Abcam

Prices $378.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IL23 Receptor antibody (ab22059) at 1 µg/mlLane 1 : Colon tissue lysate (Human) Tissue Lysate - adult normal tissue (ab30051)Lane 2 : Colon (Mouse) Tissue Lysate - normal tissue (ab29544)Lane 3 : Spleen (Human) Tissue Lysate - adult normal tissue (ab29699)Lane 4 : Spleen (Mouse) Tissue Lysate (ab29293)Lane 5 : A431 (Human epithelial carcinoma cell line) Whole Cell LysateLane 6 : Hela Whole Cell Lysate - Staurosporine Treated (24hr, 500nM) Lane 7 : NIH 3T3 (Mouse embryonic fibroblast cell line) Whole Cell Lysate (ab7179)Lane 8 : Liver (Mouse) Tissue Lysate SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-IL23 Receptor antibody - Aminoterminal end - ab53656 from Abcam

Prices $400.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab53656 at 1/250 dilution staining IL23 Receptor in human spleen by Immunohistochemistry, Paraffin embedded tissue.

Anti-IL23R Antibody (aa253-273) - LS-C47412 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-IL23R Antibody (N-Terminus) - LS-C83986 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Goat
Clonality Polyclonal

Anti-IL23R Antibody (clone 218213, PerCP) - LS-C125821 from LifeSpan Bioscience

Prices $575.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone 218213

Anti-IL23R Antibody (aa57-77) - LS-C148065 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-IL23R Antibody (aa427-457, AP) - LS-C236575 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IL23R Antibody (aa427-457, APC) - LS-C236576 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IL23R Antibody (aa427-457, PE) - LS-C236579 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IL23R Antibody (aa427-457, Biotin) - LS-C236577 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IL23R Antibody (aa427-457, FITC) - LS-C236578 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IL23R Antibody (aa24-354) - LS-C37068 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot shows lysates of K562 human chronic myelogenous leukemia cell line. PVDF membrane was probed with 2 ug/mL of LS-C37068 followed by HRP conjugated Anti Mouse IgG Secondary Antibody. A specific band was detected for IL 23 R at approximately 58 kD (as indicated). This experiment was conducted under non reducing conditions.

Anti-IL23R Antibody (aa59-87) - LS-C187852 from LifeSpan Bioscience

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry of paraffin-embeddedi mouse spleen stained with Goat anti-human IL-23 Receptor

Anti-IL23R Antibody (aa553-629) - LS-C308468 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-IL23R Antibody (aa400-470) - LS-C724 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of IL-23R in (A) Jurkat and (B) NIH3T3 cell lysate using antibody at 0.5 ug/ml.

Anti-IL23R Antibody (aa427-457) - LS-C322217 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IL23R Antibody (aa553-629, Azide-free) - LS-C327657 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-IL23R Antibody (aa427-457, Azide-free, HRP) - LS-C249266 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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