IL23R

Gene Symbol IL23R
Entrez Gene 149233
Alt Symbol -
Species Human
Gene Type protein-coding
Description interleukin 23 receptor
Other Description IL-23 receptor|interleukin-23 receptor
Swissprots Q4VGP6 Q4VGP5 Q4VGP1 Q4VGP3 Q5VWK7 C9JGX4 Q96AS1 Q4VGP2 Q8IW84 Q8NFQ9 Q5VWK5 Q4VGP4
Accessions BAJ13471 EAX06501 EAX06502 Q5VWK5 AF461422 AAM44229 AM990313 CAQ51232 AM990314 CAQ51233 AM990315 CAQ51234 AM990316 CAQ51235 AM990317 CAQ51236 AM990318 CAQ51237 AM990319 CAQ51238 AM990320 CAQ51239 AM990321 CAQ51240 AM990322 CAQ51241 AM990323 CAQ51242 AM990324 CAQ51243 AM990325 CAQ51244 AM990326 CAQ51245 AM990327 CAQ51246 AM990328 CAQ51247 AM990329 CAQ51248 AM990330 CAQ51249 AM990331 CAQ51250 AM990332 CAQ51251 AM990333 CAQ51252 AM990334 CAQ51253 AM990335 CAQ51254 AM990336 CAQ51255 AM990337 CAQ51256 AY937250 AAY18345 AY937251 AAY18346 AY937252 AAY18347 AY937253 AAY18348 AY937254 AAY18349 AY937255 AAY18350 BC016829 AAH16829 BC040720 AAH40720 BC142955 BC166698 AAI66698 FM212237 CAR79024 FM212238 CAR79025 FM212239 CAR79026 FM212240 CAR79027 FM212241 CAR79028 XM_005270516 XP_005270573 XM_011540789 XP_011539091 XM_011540790 XP_011539092 XM_011540791 XP_011539093 NM_144701 NP_653302
Function Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. {ECO:0000269|PubMed:12023369}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12023369}; Single-pass type I membrane protein {ECO:0000269|PubMed:12023369}.
Tissue Specificity Expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells. {ECO:0000269|PubMed:12023369, ECO:0000269|PubMed:16372191}.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Inflammatory bowel disease (IBD)

IL-23R CRISPR/Cas9 KO Plasmid (h) - sc-403591 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-23R HDR Plasmid (h) - sc-403591-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-23R Double Nickase Plasmid (h) - sc-403591-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-23R Double Nickase Plasmid (h2) - sc-403591-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-23R CRISPR Activation Plasmid (h) - sc-403591-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-23R CRISPR Activation Plasmid (h2) - sc-403591-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-23R Lentiviral Activation Particles (h) - sc-403591-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-23R Lentiviral Activation Particles (h2) - sc-403591-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-23R siRNA (h) - sc-60834 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-23R shRNA Plasmid (h) - sc-60834-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-23R shRNA (h) Lentiviral Particles - sc-60834-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-23 R RNAi - H00149233-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU069331 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10613 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10613 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

IL23R siRNA (Human) - CRJ5610 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IL23R - MBS8224386 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Il23r (NM_144701.2) - SHH318761 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human IL23R(NM_144701.2) - SHL172772 from Creative biogene

Category siRNA
Species Reactivities Human

Human IL23R siRNA - orb276111 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IL23R shRNA Plasmid (Human) - CHJ5610 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IL23R miRNA 3'UTR clone - MiUTR1H-04910 from Creative biogene

Species Reactivities Human
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