CBLN1

Gene Symbol CBLN1
Entrez Gene 869
Alt Symbol -
Species Human
Gene Type protein-coding
Description cerebellin 1 precursor
Other Description cerebellin-1|precerebellin
Swissprots P23435 B2RAN9 Q52M09
Accessions EAW82731 P23435 AI147523 AK314276 BAG36936 BC093692 AAH93692 BC093718 AAH93718 CN281334 M58583 AAA35676 R50764 NM_004352 NP_004343
Function Required for synapse integrity and synaptic plasticity. During cerebellar synapse formation, essential for the formation and maintenance of parallel fiber and Purkinje cell synapses. When parallel fibers make contact with Purkinje spines, CBLN1 interaction with GRID2 triggers the recruitment of NRXN1 and secretory vesicles to the sites of contact. NRXN1-CBLN1-GRID2 signaling induces presynaptic morphological changes, which may further accumulate pre- and postsynaptic components to promote bidirectional maturation of parallel fiber - Purkinje cell functionnally active synapses by a positive feedback mechanism. Required for CBLN3 export from the endoplasmic reticulum and secretion (By similarity). {ECO:0000250}.
Subcellular Location Secreted. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}.
Tissue Specificity In the Purkinje cells postsynaptic structures. In the cerebellum, cerebellin is much less abundant than [des- Ser1]-cerebellin.

Cerebellin 1 (F-14) - sc-164050 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CBLN1 antibody - ab64184 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab64184 (10ug/ml) staining human CBLN1 in human prostate tissue by immunohistochemistry using formalin-fixed, paraffin-embedded tissue.

Anti-CBLN1 antibody - ab92526 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CBLN1 antibody (ab92526) at 1/500 dilutionLane 1 : HUVEC cell extractsLane 2 : HUVEC cell extracts with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-CBLN1 antibody [EPR13649] - ab181379 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13649
All lanes : Anti-CBLN1 antibody [EPR13649] (ab181379) at 1/1000 dilutionLane 1 : Human cerebellum tissue lysateLane 2 : Human fetal brain tissue lysateLane 3 : Neuro-2a cell lysateLane 4 : U87-MG cell lysateLane 5 : SH-SY5Y cell lysateLane 6 : C6 cell lysateLane 7 : Raw 264.7 cell lysateLysates/proteins at 10 µg per lane.

Anti-CBLN1 antibody [EPR13655] - ab181219 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13655
Immunohistochemical analysis of paraffin embedded Human cerebellum tissue sections labeling CBLN1 using ab181219 at a 1/100 dilution. A ready to use HRP Polymer for Rabbit IgG was used as the secondary. Hematoxylin counterstain.

Anti-Precerebellin antibody - ab36908 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 :  Anti-Precerebellin antibody (ab36908) at 2 µg/mlLane 2 :  Anti-Precerebellin antibody (ab36908) at 4 µg/mlLane 1 : 293 cell lysate.Lane 2 : 293 cell lysate.

Anti-Precerebellin antibody - ab36909 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 :  Anti-Precerebellin antibody (ab36909) at 2 µg/mlLane 2 :  Anti-Precerebellin antibody (ab36909) at 4 µg/mlLane 1 : Mouse cerebellum cell lysate.Lane 2 : Mouse cerebellum cell lysate.Lysates/proteins at 15 µg per lane.

Anti-CBLN1 / Cerebellin 1 Antibody - LS-C121163 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CBLN1 / Cerebellin 1 Antibody (aa148-193) - LS-C313705 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CBLN1 / Cerebellin 1 Antibody (aa131-180) - LS-C119839 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HUVEC cells, using CBLN1 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CBLN1 / Cerebellin 1 Antibody (C-Terminus) - LS-C135568 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CBLN1 antibody LS-C135568 Western blot of Jurkat lysate.

Anti-CBLN1 / Cerebellin 1 Antibody (C-Terminus) - LS-C19528 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry of precerebellin in 3T3 cells with precerebellin antibody at 10 ug/ml.

Anti-CBLN1 / Cerebellin 1 Antibody IHC-plus™ - LS-B478 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CBLN1 / Precerebellin antibody IHC of mouse small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B478 concentration 10 ug/ml.

Cerebellin-1/Precerebellin Antibody - NBP1-77239 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Cerebellin-1/Precerebellin Antibody [NBP1-77239] - Mouse cerebellum lysate with precerebellin antibody at (A) 2 and (B) 4 ug/ml.

Cerebellin-1/Precerebellin Antibody - NBP1-77238 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Cerebellin-1/Precerebellin Antibody [NBP1-77238] - Western blot analysis of precerebellin in 293 cell lysate with precerebellin antibody at (A) 2 and (B) 4 ug/ml.

Cerebellin-1/Precerebellin Antibody - NBP1-68432 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Precerebellin Antibody [NBP1-68432] - Analysis of extracts from HuvEc cells, using Precerebellin Antibody. The lane on the right is treated with the synthesized peptide.

CBLN1 Polyclonal Antibody - bs-11814R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CBLN1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11814R-A350 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CBLN1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11814R-A555 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CBLN1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11814R-A647 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CBLN1 Polyclonal Antibody, Cy3 Conjugated - bs-11814R-Cy3 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CBLN1 Polyclonal Antibody, Cy5 Conjugated - bs-11814R-Cy5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CBLN1 Polyclonal Antibody, Cy5.5 Conjugated - bs-11814R-Cy5.5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CBLN1 Polyclonal Antibody, Cy7 Conjugated - bs-11814R-Cy7 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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