CBLN1

Gene Symbol	CBLN1
Entrez Gene	869
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	cerebellin 1 precursor
Other Description	cerebellin-1|precerebellin
Swissprots	P23435 B2RAN9 Q52M09
Accessions	EAW82731 P23435 AI147523 AK314276 BAG36936 BC093692 AAH93692 BC093718 AAH93718 CN281334 M58583 AAA35676 R50764 NM_004352 NP_004343
Function	Required for synapse integrity and synaptic plasticity. During cerebellar synapse formation, essential for the formation and maintenance of parallel fiber and Purkinje cell synapses. When parallel fibers make contact with Purkinje spines, CBLN1 interaction with GRID2 triggers the recruitment of NRXN1 and secretory vesicles to the sites of contact. NRXN1-CBLN1-GRID2 signaling induces presynaptic morphological changes, which may further accumulate pre- and postsynaptic components to promote bidirectional maturation of parallel fiber - Purkinje cell functionnally active synapses by a positive feedback mechanism. Required for CBLN3 export from the endoplasmic reticulum and secretion (By similarity). {ECO:0000250}.
Subcellular Location	Secreted. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}.
Tissue Specificity	In the Purkinje cells postsynaptic structures. In the cerebellum, cerebellin is much less abundant than [des- Ser1]-cerebellin.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human Precerebellin peptide - ab39851 from Abcam Category Peptide Species Human

Human Precerebellin peptide - ab39854 from Abcam Category Peptide Species Human

CBLN1 / Cerebellin 1 Antibody Blocking Peptide - LS-E30167 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CBLN1 / Cerebellin 1 Antibody Blocking Peptide - LS-E30168 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CBLN1 / Cerebellin 1 Antibody Blocking Peptide - LS-E21814 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Cerebellin-1/Precerebellin Blocking Peptide - NBP1-77239PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Cerebellin-1/Precerebellin Blocking Peptide - NBP1-77238PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Precerebellin Peptide - GTX85499-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Precerebellin Peptide - GTX85500-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Recombinant Human Cerebellin-1, CF - 6934-CB-025 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Glu22-Leu193, with an N-terminal HA (YPYDVPDYA) tag

CBLN1 peptide - orb217029 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey

CBLN1 Blocking Peptide - 33R-5207 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Cerebellin-1 - AR05030PU-N from Acris Antibodies Category Protein Prices $205.00 Sizes 100 µg Source Human Species Human

Cerebellin-1 Control Peptide - AP30690CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Cerebellin-1 Control Peptide - AP30691CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Precerebellin Peptide - 3587P from ProSci Category Peptide Species Human

Precerebellin Peptide - 3589P from ProSci Category Peptide Species Human

CBLN1 fusion protein - ag12856 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

CBLN1 fusion protein - Ag12835 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Cerebellin Peptide - 350125 from ABBIOTEC Category Peptide Prices $145.00 Sizes 1 mg

SYNTHETIC HUMAN CEREBELLIN - GWB-7C45AE from Genway Biotech Category Peptide Prices $184.00 Sizes 100 µg Species Human

Recombinant Cerebellin 1 (CBLN1) - RPG300Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Cerebellin 1 Blocking Peptide - CBP1166 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Monkey, Pig

Cerebellin 1 Peptide - BS5658P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Cbln1 - pro10216 from Covalab Category Protein Source HEK 293 cells Species Human

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