| Gene Symbol |
MDGA1
|
| Entrez Gene |
266727
|
| Alt Symbol |
GPIM, MAMDC3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MAM domain containing glycosylphosphatidylinositol anchor 1
|
| Other Description |
GPI and MAM protein|MAM domain-containing glycosylphosphatidylinositol anchor protein 1|MAM domain-containing protein 3|glycosyl-phosphatidyl-inositol-MAM|glycosylphosphatidylinositol-MAM
|
| Swissprots |
Q8NBE3 A6NHG0 Q8NFP4
|
| Accessions |
EAX03950 EAX03951 EAX03952 EAX03953 EAX03954 Q8NFP4 AF478693 AAM77220 AK055376 AK090677 BAC03502 AK091149 AK091650 AK092308 AK126965 BC152817 AAI52818 BC156659 AAI56660 BX647180 BX647253 XM_006715056 XP_006715119 XM_006715057 XP_006715120 XR_926140 XR_926141 XR_926142 NM_153487 NP_705691
|
| Function |
Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity). Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2. {ECO:0000250, ECO:0000269|PubMed:23248271}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:15922729}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:15922729}. Note=Associated with lipid rafts.
|
| Tissue Specificity |
Has been found in brain, heart, skeletal muscle and kidney. Found to be overexpressed in tumor tissues.
|