Gene Symbol | MDGA1 |
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Entrez Gene | 266727 |
Alt Symbol | GPIM, MAMDC3 |
Species | Human |
Gene Type | protein-coding |
Description | MAM domain containing glycosylphosphatidylinositol anchor 1 |
Other Description | GPI and MAM protein|MAM domain-containing glycosylphosphatidylinositol anchor protein 1|MAM domain-containing protein 3|glycosyl-phosphatidyl-inositol-MAM|glycosylphosphatidylinositol-MAM |
Swissprots | Q8NBE3 A6NHG0 Q8NFP4 |
Accessions | EAX03950 EAX03951 EAX03952 EAX03953 EAX03954 Q8NFP4 AF478693 AAM77220 AK055376 AK090677 BAC03502 AK091149 AK091650 AK092308 AK126965 BC152817 AAI52818 BC156659 AAI56660 BX647180 BX647253 XM_006715056 XP_006715119 XM_006715057 XP_006715120 XR_926140 XR_926141 XR_926142 NM_153487 NP_705691 |
Function | Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity). Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2. {ECO:0000250, ECO:0000269|PubMed:23248271}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:15922729}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:15922729}. Note=Associated with lipid rafts. |
Tissue Specificity | Has been found in brain, heart, skeletal muscle and kidney. Found to be overexpressed in tumor tissues. |
Recombinant Human MDGA1, CF - 5055-MD-050 from R&D Systems
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Recombinant Human MAM Domain Containing Glycosylphosphatidylinositol Anchor 1, His-tagged - MDGA1-5686H from Creative Biomart
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Recombinant Human MAM domain-containing glycosylphosphatidylinositol anchor prot - CSB-YP850880HU CSB-EP850880HU CSB-BP850880HU CSB-MP850880HU from Cusabio
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Recombinant Human MDGA1 Protein, CF - 5055-MD from R&D Systems
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MDGA1 Protein - NBP1-93712PEP from Novus Biologicals
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MDGA1 Recombinant Protein Antigen - NBP2-38624PEP from Novus Biologicals
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MDGA1 Peptide, Human - M34GP09335H from Creative Peptides
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MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (MDGA1), partial, Recombinant Protein - MBS1390460 from MyBioSource
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Recombinant Mouse MDGA1 Protein, CF - 7587-MD from Novus Biologicals
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