FBXL21

Gene Symbol FBXL21
Entrez Gene 26223
Alt Symbol FBL3B, FBXL3B, FBXL3P, Fbl21
Species Human
Gene Type protein-coding
Description F-box and leucine-rich repeat protein 21 (gene/pseudogene)
Other Description F-box and leucine-rich repeat protein 3 pseudogene|F-box and leucine-rich repeat protein 3B|F-box protein Fbl3b|F-box/LRR-repeat protein 21|F-box/LRR-repeat protein 3B
Swissprots Q9UKT6
Accessions EAW62202 EAW62203 Q9UKT6 AF129533 AAF04467 BC044938 BC106753 AAI06754 DA633926 NM_012159 NP_036291
Function Substrate-recognition component of the SCF(FBXL21) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL21) complex mainly acts in the cytosol and mediates ubiquitination of CRY proteins (CRY1 and CRY2), leading to CRY proteins stabilization. The SCF(FBXL21) complex counteracts the activity of the SCF(FBXL3) complex and protects CRY proteins from degradation. Involved in the hypothalamic suprachiasmatic nucleus (SCN) clock regulating temporal organization of the daily activities (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}. Note=Mainly localizes in the cytosol. Present at low level in the nucleus (By similarity). {ECO:0000250}.

FBL3B (N-17) - sc-54459 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

FBL3B (S-18) - sc-54493 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-FBXL21 antibody - ab196292 from Abcam

Prices $370.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-FBXL21 antibody (ab196292) at 1/500 dilutionLane 1 : Human fetal liver lysateLane 2 : Human fetal kidney lysate

Anti-FBXL21 antibody - ab57302 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57302 FBXL21 antibody at 1ug/ml.

Anti-FBXL21 Antibody (aa1-138) - LS-C179103 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXL21 Antibody (aa167-277) - LS-C307491 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

FBXL21 Antibody (4A1) - H00026223-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A1

FBXL21 Antibody - H00026223-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

FBXL21 Polyclonal Antibody - bs-8476R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-FBXL21 antibody produced in mouse - WH0026223M2 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A1
<B>Immunoblotting</B><BR/>Monoclonal Anti-FBXL21, <B>Cat. No. WH0026223M2</B> used at the antibody concentration: 1 μg/mL. Specific band of ~38.21 kDa using immunogen protein lysate.

FBXL21 antibody - orb78427 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of fetal liver and fetal kidney lysate using FBXL21 antibody

FBXL21 Antibody - abx037126 from Abbexa

Host Rabbit
Clonality Polyclonal

FBXL21 antibody - H00026223-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

FBXL21 antibody - H00026223-M02 from Acris Antibodies

Prices $360.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A1

FBXL21 Antibody - 39858 from Signalway Antibody

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FBXL21 Antibody - E306549 from Enogene

Prices $275.00
Sizes 100μg/200μl

Anti-FBXL21 (aa 167-276) polyclonal antibody - DPAB-DC1282 from Creative Diagnostics

Host Mouse
Clonality Polyclonal

FBXL21, Polyclonal Antibody - MBS8501114 from MyBioSource

Prices $330.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

FBXL21, Polyclonal Antibody - MBS415945 from MyBioSource

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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