LRRC4

Gene Symbol LRRC4
Entrez Gene 64101
Alt Symbol NAG14, NGL-2
Species Human
Gene Type protein-coding
Description leucine rich repeat containing 4
Other Description brain tumor associated protein LRRC4|brain tumor-associated protein BAG|leucine-rich repeat-containing 4|leucine-rich repeat-containing protein 4|nasopharyngeal carcinoma-associated gene 14 protein|netrin-G2 ligand
Swissprots Q6ZMI8 Q9HBW1 Q14DU9 Q96A85 A4D0Y9
Accessions EAL24316 EAW83639 Q9HBW1 AF196976 AAG28019 AI568859 AJ297858 CAC82651 AK172751 BAD18737 AK314047 BAG36756 AY358307 AAQ88674 BC036685 BC111561 AAI11562 BC111745 AAI11746 BU682120 XM_011516461 XP_011514763 NM_022143 NP_071426
Function Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. Note=LRRC4 and DLG4 are interdependent for synaptic localization. {ECO:0000250}.
Tissue Specificity Specifically expressed in brain. {ECO:0000269|PubMed:15967442}.
Top Pathways Axon guidance, Cell adhesion molecules (CAMs)

LRRC4 (C-11) - sc-376475 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LRRC4 (C-11): sc-376475. Western blot analysis of LRRC4 expression in IMR-32 whole cell lysate.

LRRC4 (C-13) - sc-104357 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LRRC4 (H-68) - sc-98630 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LRRC4 (H-68): sc-98630. Western blot analysis of LRRC4 expression in human brain hippocampus tissue extract.

LRRC4 (N-16) - sc-104359 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LRRC4 (T-15) - sc-104360 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Netrin G2 Ligand antibody - ab116697 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Netrin G2 Ligand antibody (ab116697) at 1 µg/mlLane 1 : Brain (Mouse) Tissue Lysate Lane 2 : Mouse Hippocampus Tissue LysateLane 3 : Forebrain (Mouse) Tissue LysateLane 4 : Mouse Cortex Tissue LysateLane 5 : U-87 MG (Human glioblastoma astrocytoma) Whole Cell Lysate - Negative controlLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Netrin G2 Ligand antibody - ab102927 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Netrin G2 Ligand antibody (ab102927) at 1/100 dilution + K562 cell line lysate at 35 µg

Anti-Netrin G2 Ligand antibody [MM0804-9H61] - ab201931 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0804-9H61

Anti-LRRC4 Antibody (aa39-527, clone 12K125) - LS-C182898 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 12K125

Anti-LRRC4 Antibody (aa531-559, AP) - LS-C223094 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC4 Antibody (aa531-559, APC) - LS-C223095 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC4 Antibody (aa531-559, Biotin) - LS-C226838 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC4 Antibody (aa531-559, FITC) - LS-C226840 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC4 Antibody (aa531-559, Azide-free, HRP) - LS-C226841 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC4 Antibody (aa531-559, PE) - LS-C226842 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC4 Antibody (aa536-565) - LS-C322732 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC4 Antibody (aa531-559) - LS-C165881 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with LRRC4 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

LRRC4 Antibody - AF4995 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
LRRC4 was detected in immersion fixed paraffin-embedded sections of human brain (cerebellum) using 15 µg/mL Sheep Anti-Human LRRC4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4995) overnight at 4 °C. Tissue was stained with the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS019) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

LRRC4 Antibody (701424) - MAB4995 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 701424
Western blot shows lysates of human brain (hypothalamus) tissue and mouse brain tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human LRRC4 Monoclonal Antibody (Catalog # MAB4995) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for LRRC4 at approximately 80 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

LRRC4 Antibody (701419) - MAB49951 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 701419

LRRC4 Antibody - NBP2-30399 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: LRRC4 Antibody [NBP2-30399] - Immunohistochemical staining of human stomach, upper shows strong cytoplasmic positivity in glandular cells.

LRRC4 Polyclonal Antibody - bs-1974R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ANTI-LRRC4 (C-TERM) antibody produced in rabbit - SAB1301490 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>LRRC4 (C-term): <B>Cat. No. SAB1301490</B>: LRRC4 in Human brain tissue with LRRC4 antibody (C-term) at 5 μg/mL.

LRRC4-Antibody-C-term - AP9530b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of LRRC4 Antibody (C-term) (Cat. #AP9530b) in K562 cell line lysates (35ug/lane). LRRC4 (arrow) was detected using the purified Pab.

LRRC4 Antibody - C-terminal region (OAAB06127) - OAAB06127 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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