LRRC4

Gene Symbol LRRC4
Entrez Gene 64101
Alt Symbol NAG14, NGL-2
Species Human
Gene Type protein-coding
Description leucine rich repeat containing 4
Other Description brain tumor associated protein LRRC4|brain tumor-associated protein BAG|leucine-rich repeat-containing 4|leucine-rich repeat-containing protein 4|nasopharyngeal carcinoma-associated gene 14 protein|netrin-G2 ligand
Swissprots Q6ZMI8 Q9HBW1 Q14DU9 Q96A85 A4D0Y9
Accessions EAL24316 EAW83639 Q9HBW1 AF196976 AAG28019 AI568859 AJ297858 CAC82651 AK172751 BAD18737 AK314047 BAG36756 AY358307 AAQ88674 BC036685 BC111561 AAI11562 BC111745 AAI11746 BU682120 XM_011516461 XP_011514763 NM_022143 NP_071426
Function Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. Note=LRRC4 and DLG4 are interdependent for synaptic localization. {ECO:0000250}.
Tissue Specificity Specifically expressed in brain. {ECO:0000269|PubMed:15967442}.
Top Pathways Axon guidance, Cell adhesion molecules (CAMs)

LRRC4 CRISPR/Cas9 KO Plasmid (h) - sc-410090 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC4 HDR Plasmid (h) - sc-410090-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC4 Double Nickase Plasmid (h) - sc-410090-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC4 Double Nickase Plasmid (h2) - sc-410090-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC4 CRISPR Activation Plasmid (h) - sc-410090-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC4 CRISPR Activation Plasmid (h2) - sc-410090-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC4 Lentiviral Activation Particles (h) - sc-410090-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC4 Lentiviral Activation Particles (h2) - sc-410090-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC4 siRNA (h) - sc-89808 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LRRC4 shRNA Plasmid (h) - sc-89808-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LRRC4 shRNA (h) Lentiviral Particles - sc-89808-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU025441 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12738 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12738 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

LRRC4 siRNA (Human) - CRJ1920 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LRRC4 (NM_022143.4) - SHH334523 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human LRRC4(NM_022143.4) - SHH162731 from Creative biogene

Category siRNA
Species Reactivities Human

LRRC4 shRNA Plasmid (Human) - CHJ1920 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LRRC4 miRNA 3'UTR clone - MiUTR1H-05920 from Creative biogene

Species Reactivities Human
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