LRRC4

Gene Symbol LRRC4
Entrez Gene 64101
Alt Symbol NAG14, NGL-2
Species Human
Gene Type protein-coding
Description leucine rich repeat containing 4
Other Description brain tumor associated protein LRRC4|brain tumor-associated protein BAG|leucine-rich repeat-containing 4|leucine-rich repeat-containing protein 4|nasopharyngeal carcinoma-associated gene 14 protein|netrin-G2 ligand
Swissprots Q6ZMI8 Q9HBW1 Q14DU9 Q96A85 A4D0Y9
Accessions EAL24316 EAW83639 Q9HBW1 AF196976 AAG28019 AI568859 AJ297858 CAC82651 AK172751 BAD18737 AK314047 BAG36756 AY358307 AAQ88674 BC036685 BC111561 AAI11562 BC111745 AAI11746 BU682120 XM_011516461 XP_011514763 NM_022143 NP_071426
Function Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. Note=LRRC4 and DLG4 are interdependent for synaptic localization. {ECO:0000250}.
Tissue Specificity Specifically expressed in brain. {ECO:0000269|PubMed:15967442}.
Top Pathways Axon guidance, Cell adhesion molecules (CAMs)

Human Netrin G2 Ligand protein fragment - ab151932 from Abcam

Category Protein
Source HEK 293 cells
Species Human

LRRC4 Antibody Blocking Peptide - LS-E10181 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

LRRC4-Antibody-C-term-Blocking-Peptide - BP9530b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human LRRC4, CF - 4995-LR-050 from R&D Systems

Category Protein
Source Chinese Hamster Ovary cell line, CHO-derived, Ala39-Lys527, with a C-terminal 6-His tag

Human LRRC4 protein - orb49507 from Biorbyt

Category Protein
Prices $264.00, $340.00, $1,751.00, $2,474.00
Sizes 10 μg, 50 μg, 500 μg, 1 mg
Source HEK293

Leucine-Rich Repeat-Containing Protein 4, LRRC4, Human, Recombinant - 19-C486 from ARP American Research Products

Category Protein
Prices $109.00
Sizes 10 µg
Source HEK293
Species Human

NGL 2 Recombinant Protein - 96-523 from ProSci

Category Protein
Prices $425.00
Sizes 100 µg
Source HEK293 cells
Species Human
The purity of rh LRRC4 was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

LRRC4 fusion protein - ag9396 from Proteintech Group

Category Protein
Source E. coli-derived,
Species Human

LRRC4 fusion protein - ag16521 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

LRRC4 fusion protein - ag20376 from Proteintech Group

Category Protein
Source E. coli-derived, PET30a
Species Human

LRRC4 fusion protein - ag17061 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human LRRC4 Protein - BP001761-C486 from Syd Labs

Category Protein
Prices $98.00, $264.00, $2,640.00
Sizes 10 µg, 50 µg, 1 mg
Source HEK 293-derived.
Species Human

Recombinant Human Leucine Rich Repeat Containing 4, His-tagged - LRRC4-5680H from Creative Biomart

Category Protein
Source Chinese HamsterOvary cell line, CHO-derived.

Human LRRC4 Protein - LR4-H5221 from ACROBiosystems

Category Protein
Prices $290.00, $1,800.00
Sizes 100 µg, 1 mg (500ug x 2)
Source Human LRRC4, His Tag (LR4-H5221) is expressed from human 293 cells (HEK293). It contains AA Ala 39 - Lys 527 (Accession # AAI11562.1).
Species Human

Recombinant Human Leucine-rich repeat-containing protein 4(LRRC4) - CSB-YP867195HU CSB-EP867195HU CSB-BP867195HU CSB-MP867195HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Human CellExp™ LRRC4 /NGL-2, human recombinant - 7461-10 from Biovision

Category Protein
Prices $195.00
Sizes 10 μg
Source HEK293 cells
Species Human

Human CellExp™ LRRC4 /NGL-2, human recombinant - 7461-50 from Biovision

Category Protein
Prices $595.00
Sizes 50 μg
Source HEK293 cells
Species Human

Recombinant Human LRRC4 Protein, CF - 4995-LR from R&D Systems

Category Protein
Prices $329.00
Sizes 50 µg
Source Chinese Hamster Ovary cell line, CHO-derived Ala39-Lys527, with a C-terminal 6-His tag
Species Human

LRRC4 Recombinant Protein Antigen - NBP2-30399PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Source E.coli
Species Human

LRRC4 Peptide, Human - M34GP08903H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Human CellExp™ LRRC4 /NGL-2, human recombinant - 7461 from Biovision

Category Protein
Prices $205.00, $615.00
Sizes 10 μg, 50 μg
Source HEK293 cells
Species Human

Recombinant Human LRRC4 Fc Chimera Protein, CF - 9375-LR from R&D Systems

Category Protein
Prices $329.00
Sizes 50 µg
Source Human embryonic kidney cell, HEK293-derived Human LRRC4 (Ala39-Lys527) Accession # Q9HBW1 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus
Species Human
When Recombinant Mouse Netrin‑G2a Fc Chimera (Catalog # 2744-NG ) is coated at 1 µg/mL,Recombinant Human LRRC4 Fc Chimera (Catalog # 9375-LR) binds with an ED 50 = 2-12 ng/mL.

Human CellExp™ LRRC4 /NGL-2, Human recombinant - 268-11062-1 from RayBiotech

Category Protein
Species Human

Leucine-rich repeat-containing protein 4 (LRRC4), Recombinant Protein - MBS1285129 from MyBioSource

Category Protein
Prices $1,275.00, $1,275.00, $1,495.00, $1,495.00, $2,085.00, $2,085.00, $2,550.00, $2,550.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

LRRC4/NGL-2, Recombinant Protein - MBS844933 from MyBioSource

Category Protein
Prices $255.00, $675.00
Sizes 10 µg, 50 µg
Source HEK293 cells
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