Gene Symbol | SNRPD2 |
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Entrez Gene | 6633 |
Alt Symbol | SMD2, SNRPD1, Sm-D2 |
Species | Human |
Gene Type | protein-coding |
Description | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa |
Other Description | small nuclear ribonucleoprotein Sm D2|snRNP core protein D2 |
Swissprots | J3KPM5 P62316 A8K797 |
Accessions | AAD22673 CAE94072 EAW57373 EAW57374 P62316 AJ707552 AK291912 BAF84601 BC000486 AAH00486 BC001930 AAH01930 BG528418 BU532756 CB136390 DA325073 DQ891246 ABM82172 DQ894432 ABM85358 U15008 AAC13776 XM_005259180 XP_005259237 NM_004597 NP_004588 NM_177542 NP_808210 |
Function | Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. {ECO:0000269|PubMed:18984161, ECO:0000269|PubMed:23333303}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:18984161}. Nucleus {ECO:0000269|PubMed:18984161}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. |
Top Pathways | Spliceosome |
Human-SNRPD2-cDNA-Clone - DC00229 from Abgent, a WuXi AppTec company
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SNRPD2 - MBS1274913 from MyBioSource
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Human SNRPD2 ORF Clone(NM_004597.5) - CDCL176544 from Creative Biomart
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human SNRPD2 ORF clone - CDCH084064 from Creative Biomart
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human SNRPD2 ORF clone - CDCH084065 from Creative Biomart
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human SNRPD2 ORF clone - CDCH084066 from Creative Biomart
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human SNRPD2 ORF clone - CDCH084067 from Creative Biomart
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human SNRPD2 ORF clone (NM_177542.2) - CDCH084066 from Creative biogene
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Human SNRPD2 ORF Clone (BC000486) - CDCS411871 from Creative biogene
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