Gene Symbol | SNRPD2 |
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Entrez Gene | 6633 |
Alt Symbol | SMD2, SNRPD1, Sm-D2 |
Species | Human |
Gene Type | protein-coding |
Description | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa |
Other Description | small nuclear ribonucleoprotein Sm D2|snRNP core protein D2 |
Swissprots | J3KPM5 P62316 A8K797 |
Accessions | AAD22673 CAE94072 EAW57373 EAW57374 P62316 AJ707552 AK291912 BAF84601 BC000486 AAH00486 BC001930 AAH01930 BG528418 BU532756 CB136390 DA325073 DQ891246 ABM82172 DQ894432 ABM85358 U15008 AAC13776 XM_005259180 XP_005259237 NM_004597 NP_004588 NM_177542 NP_808210 |
Function | Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. {ECO:0000269|PubMed:18984161, ECO:0000269|PubMed:23333303}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:18984161}. Nucleus {ECO:0000269|PubMed:18984161}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. |
Top Pathways | Spliceosome |
Human SNRPD2 full length protein - ab104481 from Abcam
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Human SNRPD2 full length protein - ab125645 from Abcam
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SNRPD1 / SMD1 Antibody Blocking Peptide - LS-E14906 from LifeSpan Bioscience
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SNRPD1 / SMD1 Antibody Blocking Peptide - LS-E14907 from LifeSpan Bioscience
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SNRPD1 / SMD1 Antibody Blocking Peptide - LS-E7144 from LifeSpan Bioscience
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SNRPD1 / SMD1 Antibody Blocking Peptide - LS-E7143 from LifeSpan Bioscience
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SNRPD2 Antibody Blocking Peptide - LS-E14810 from LifeSpan Bioscience
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SNRPD2 Antibody Blocking Peptide - LS-E14811 from LifeSpan Bioscience
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SNRPD2 Antibody Blocking Peptide - LS-E8492 from LifeSpan Bioscience
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SNRPD2 Recombinant Protein - H00006633-P01 from Novus Biologicals
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Recombinant Human SNRPD2 Protein - NBP1-51012 from Novus Biologicals
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SNRPD2-Antibody-N-term-Blocking-Peptide - BP6841a from Abgent, a WuXi AppTec company
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Human SNRPD2 protein - orb169325 from Biorbyt
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Human SNRPD1 protein - orb169323 from Biorbyt
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Human SNRPD2 protein - orb245142 from Biorbyt
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Human SNRPD2 protein - orb169324 from Biorbyt
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SNRPD1 Blocking Peptide - 33R-6711 from Fitzgerald
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SNRPD2 Blocking Peptide - 33R-2619 from Fitzgerald
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SNRPD2 Blocking Peptide - 33R-6463 from Fitzgerald
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SNRPD2 protein (His tag) - 80R-1695 from Fitzgerald
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snRNP-D2 / Sm-D2 (1-118, His-tag) - AR09877PU-L from Acris Antibodies
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snRNP-D2 / Sm-D2 (1-118, His-tag) - AR09877PU-N from Acris Antibodies
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snRNP-D2 / Sm-D2 - H00006633-P01 from Acris Antibodies
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snRNP-D2 / Sm-D2 - H00006633-P01-10 from Acris Antibodies
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snRNP-D2 / Sm-D2 - H00006633-P01-25 from Acris Antibodies
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