SNRPD2

Gene Symbol SNRPD2
Entrez Gene 6633
Alt Symbol SMD2, SNRPD1, Sm-D2
Species Human
Gene Type protein-coding
Description small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
Other Description small nuclear ribonucleoprotein Sm D2|snRNP core protein D2
Swissprots J3KPM5 P62316 A8K797
Accessions AAD22673 CAE94072 EAW57373 EAW57374 P62316 AJ707552 AK291912 BAF84601 BC000486 AAH00486 BC001930 AAH01930 BG528418 BU532756 CB136390 DA325073 DQ891246 ABM82172 DQ894432 ABM85358 U15008 AAC13776 XM_005259180 XP_005259237 NM_004597 NP_004588 NM_177542 NP_808210
Function Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. {ECO:0000269|PubMed:18984161, ECO:0000269|PubMed:23333303}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:18984161}. Nucleus {ECO:0000269|PubMed:18984161}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Top Pathways Spliceosome

Sm D2 (E-14) - sc-240900 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SNRPD2 antibody [EPR16762] - ab198296 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16762
All lanes : Anti-SNRPD2 antibody [EPR16762] (ab198296) at 1/20000 dilutionLane 1 : HepG2 cell lysateLane 2 : MCF7 cell lysateLane 3 : A549 cell lysateLane 4 : HeLa cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilutiondeveloped using the ECL technique

Anti-SNRPD2 Antibody (FITC) - LS-C210771 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SNRPD2 Antibody (HRP) - LS-C210772 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SNRPD2 Antibody (Biotin) - LS-C211550 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SNRPD2 Antibody (N-Terminus) - LS-C101853 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SNRPD2 antibody LS-C101853 Western blot of Jurkat lysate.

Anti-SNRPD2 Antibody (C-Terminus) - LS-C101854 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SNRPD2 antibody LS-C101854 Western blot of HepG2 cell lysate.

Anti-SNRPD2 Antibody - LS-C333070 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Mouse pancreas cell lines, using SNRPD2 antibody.

Anti-SNRPD2 Antibody - LS-C346167 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of MCF7 cell using SNRPD2 antibody. Blue: DAPI for nuclear staining.

Anti-SNRPD2 Antibody (aa1-30) - LS-C161355 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with SNRPD2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-SNRPD2 Antibody IHC-plus™ - LS-B11357 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SNRPD2 antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11357 concentration 20 ug/ml.

SNRPD2 Antibody - NBP2-20438 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SNRPD2 Antibody [NBP2-20438] - Sample (30 ug of whole cell lysate) A: A549 15% SDS PAGE gel, diluted at 1:1000.

SNRPD2 Antibody - NBP1-87028 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: SNRPD2 Antibody [NBP1-87028] - Staining of human stomach shows strong nuclear positivity in glandular cells.

SNRPD2 Antibody - NBP1-57174 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SNRPD2 Antibody [NBP1-57174] - Human Jurkat, Antibody Dilution: 1.0 ug/ml SNRPD2 is supported by BioGPS gene expression data to be expressed in Jurkat.

SNRPD2 Antibody - NBP1-57173 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SNRPD2 Antibody [NBP1-57173] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

Hepatitis C Virus Core Antigen Antibody (B057M) - NB110-68196 from Novus Biologicals

Prices $299.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone B057M

Hepatitis C Virus Core Antigen Antibody (B056M) - NB110-68197 from Novus Biologicals

Prices $279.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone B056M

Hepatitis C Virus Core Antigen Antibody (B055M) - NB110-68198 from Novus Biologicals

Prices $529.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone B055M

Anti-SNRPD2 (86-100) antibody produced in rabbit - SAB1100985 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-SNRPD2 (86-100) (RB): <B>Cat. No. SAB1100985</B>: Immunofluorescence of HUVEC cells using SNRPD2 (86-100) (RB), Cat. No. SAB1100985 (red) at a 1:100 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-SNRPD2 antibody produced in rabbit - HPA041437 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SNRPD2: <B>Cat. No. HPA041437</B>: Immunohistochemical staining of human stomach shows strong nuclear positivity in glandular cells.

Anti-SNRPD2 (66-80) antibody produced in rabbit - SAB1100984 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>ANTI-SNRPD2 (66-80): <B>Cat. No. SAB1100984</B>: Immunofluorescence of HUVEC cells using SNRPD2 (66-80), Cat. No. SAB1100984 (red) at a 1:100 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-SNRPD2, (N-terminal) antibody produced in rabbit - SAB2103018 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SNRPD2, antibody produced in rabbit: <B>Cat. No. SAB2103018</B>: Immunoblotting analysis of SNRPD2 in Jurkat cell lysate with SNRPD2 anitbody at 1 μg/mL.

Anti-SNRPD2 antibody produced in rabbit - SAB2102257 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SNRPD2: <B>Cat. No.SAB2102257</B>: SNRPD2 in HepG2 cell lysate with SNRPD2 antibody at 1.0 μg/mL.

SNRPD2 antibody - N-terminal region (ARP40532_P050) - ARP40532_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SNRPD2 antibody - middle region (ARP40533_P050) - ARP40533_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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