Gene Symbol | PGAP3 |
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Entrez Gene | 93210 |
Alt Symbol | AGLA546, CAB2, PERLD1, PP1498, hCOS16 |
Species | Human |
Gene Type | protein-coding |
Description | post-GPI attachment to proteins 3 |
Other Description | COS16 homolog|gene coamplified with ERBB2 protein|per1-like domain containing 1|post-GPI attachment to proteins factor 3 |
Swissprots | Q86Z03 Q96FM1 Q8NBJ8 B4DGK7 |
Accessions | EAW60589 EAW60590 EAW60591 EAW60592 EAW60593 EAW60594 Q96FM1 AB088396 BAC55580 AF217980 AAG17223 AK057911 AK075473 AK075474 BAC11642 AK289612 BAF82301 AK294639 BAG57818 AK301106 BAG62705 AK314469 AL833198 AY358437 AAQ88803 BC010652 AAH10652 BG472165 DC389056 XM_011525480 XP_011523782 XM_011525481 XP_011523783 XR_934601 NM_001291726 NP_001278655 NM_001291728 NP_001278657 NM_001291730 NP_001278659 NM_001291732 NP_001278661 NM_001291733 NP_001278662 NM_033419 NP_219487 |
Function | Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI (Probable). {ECO:0000305|PubMed:17021251}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305|PubMed:12460457}; Multi-pass membrane protein {ECO:0000305|PubMed:12460457}. Endoplasmic reticulum membrane {ECO:0000305|PubMed:12460457}; Multi-pass membrane protein {ECO:0000305|PubMed:12460457}. Note=Mainly localizes to Golgi apparatus. {ECO:0000305}. |
Tissue Specificity | Ubiquitously expressed, with highest levels in thyroid and placenta. {ECO:0000269|PubMed:12460457}. |
Human PGAP3 full length protein - ab164935 from Abcam
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PGAP3 / PERLD1 Antibody Blocking Peptide - LS-E2295 from LifeSpan Bioscience
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PGAP3 / PERLD1 Antibody Blocking Peptide - LS-E18128 from LifeSpan Bioscience
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PGAP3 / PERLD1 Antibody Blocking Peptide - LS-E18129 from LifeSpan Bioscience
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Recombinant Human PGAP3 Protein - H00093210-P01 from Novus Biologicals
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PGAP3-Antibody-Center-Blocking-peptide - BP13237c from Abgent, a WuXi AppTec company
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PERLD1 Blocking Peptide - 33R-2299 from Fitzgerald
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PERLD1 Blocking Peptide - 33R-1204 from Fitzgerald
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PGAP3 - H00093210-P01 from Acris Antibodies
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PGAP3 control peptide - AP10144CP-N from Acris Antibodies
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PGAP3 control peptide - AP10145CP-N from Acris Antibodies
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PGAP3 control peptide - AP10146CP-N from Acris Antibodies
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PERLD1 fusion protein - ag10796 from Proteintech Group
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PERLD1 fusion protein - ag10459 from Proteintech Group
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PGAP3 Recombinant Protein Antigen - NBP1-86692PEP from Novus Biologicals
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PGAP3 Peptide, Human - M34GP11644H from Creative Peptides
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Post-GPI attachment to proteins factor 3 (PGAP3), Recombinant Protein - MBS7026076 from MyBioSource
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