STEAP4

Gene Symbol STEAP4
Entrez Gene 79689
Alt Symbol STAMP2, TIARP, TNFAIP9
Species Human
Gene Type protein-coding
Description STEAP family member 4
Other Description metalloreductase STEAP4|six transmembrane prostate protein 2|six-transmembrane epithelial antigen of prostate 4|sixTransMembrane protein of prostate 2|tumor necrosis factor, alpha-induced protein 9|tumor necrosis-alpha-induced adipose-related protein
Swissprots Q8WWB0 Q687X4 Q658Q9 Q9H5R1 Q687X5
Accessions CAJ55791 CAJ90615 CAK32295 EAW76906 EAW76907 Q687X5 AF423422 AAQ04063 AF423423 AAQ04064 AK026806 BAB15559 AK027807 AK307644 AL832955 AL833044 CAH56271 AL833671 BC020600 AAH20600 DA977808 DB162772 DC333286 NM_001205315 NP_001192244 NM_001205316 NP_001192245 NM_024636 NP_078912
Function Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation. {ECO:0000250, ECO:0000269|PubMed:18381574, ECO:0000269|PubMed:18430367, ECO:0000269|PubMed:19660107, ECO:0000269|PubMed:19787193}.
Subcellular Location Cell membrane. Golgi apparatus membrane; Multi-pass membrane protein.
Tissue Specificity Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages. {ECO:0000269|PubMed:15897894, ECO:0000269|PubMed:16227996, ECO:0000269|PubMed:18381574, ECO:0000269|PubMed:18430367, ECO:0000269|PubMed:19289123, ECO:0000269|PubMed:19660107}.

STAMP2 (C-12) - sc-104671 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
STAMP2 (C-12): sc-104671. Western blot analysis of STAMP2 expression in human adipose tissue extract.

STAMP2 (T-15) - sc-104675 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-STEAP4 antibody - ab113230 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab113230, at 10µg/ml, staining STEAP4 in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry.

Anti-STEAP4 antibody - ab63967 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-STEAP4 antibody (ab63967) at 0.3 µg/ml + Human Adipose lysate at 35 µg

Anti-STEAP4 antibody - N-terminal - ab140951 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human pancreas tissue labelling STEAP4 with ab140951 at 2.5 µg/ml after heat-induced antigen retrieval.

Anti-STEAP4 Antibody (aa301-350) - LS-C81471 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-STEAP4 Antibody (aa201-250) IHC-plus™ - LS-B4904 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STEAP4 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4904 concentration 10 ug/ml.

Anti-STEAP4 Antibody (N-Terminus) IHC-plus™ - LS-A9773 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STEAP4 antibody LS-A9773 IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-STEAP4 Antibody (Internal) IHC-plus™ - LS-B1407 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STEAP4 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1407 concentration 5 ug/ml.

Anti-STEAP4 Antibody - LS-C75988 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-STEAP4 Antibody (C-Terminus) - LS-C55534 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.3 ug/ml) staining of Human Adipose lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

STAMP2/STEAP4 Antibody - NB100-80831 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: STAMP2/STEAP4 Antibody [NB100-80831] - Rat liver tissue lysate.

STAMP2/STEAP4 Antibody (418714) - MAB4626 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 418714
Flow Cytometry STAMP2/STEAP4 Antibody (418714)

STAMP2/STEAP4 Antibody - NBP1-68081 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: STEAP4 Antibody [NBP1-68081] - Analysis of HeLa cells, using STEAP4 Antibody. The picture on the right is treated with the synthesized peptide.

STAMP2/STEAP4 Antibody - NB100-68162 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: STAMP2/STEAP4 Antibody [NB100-68162] - HEK293 overexpressing Dudulin4 and probed with (mock transfection in first lane).

Anti-STEAP4 antibody produced in rabbit - SAB4503167 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>STEAP4 Antibody: <B>Cat. No. SAB4503167</B>: Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using STEAP4 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-STEAP4 antibody produced in rabbit - SAB2900285 from Sigma-Aldrich

Prices $464.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-STEAP4: <B>Cat. No.SAB2900285</B>: Heart: Formalin-Fixed Paraffin-Embedded (FFPE).

Anti-STEAP4 antibody produced in rabbit - PRS4313 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-STEAP4: <B>Cat. No. PRS4313</B> Western blot analysis of STEAP4 in rat liver tissue lysate with STEAP4 antibody at (A) 0.5 and (B) 1 μg/mL.

Anti-STEAP4 antibody produced in rabbit - AV49842 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: Jurkat (<B>Cat. No. AV49842</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1.0 μg/mL in cell type Jurkat

Anti-STEAP4/DUDULIN4 antibody produced in goat - SAB2500995 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-STEAP4 / Dudulin4: <B>Cat. No. SAB2500995</B>: (0.3 μg/mL) staining of Human Adipose lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

STEAP4 antibody - C-terminal region (ARP49842_P050) - ARP49842_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

STEAP4--Dudulin4-Antibody - AF2041a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF2041a (0.3 µg/ml) staining of Human Adipose lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Human STAMP2 Antibody - MAB4626 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 418714
Detection of STAMP2 in Human STAMP2 Transfected HEK293 Human Cell Line by Flow Cytometry. Human STAMP2 transfected HEK293 human cell line was stained with Mouse Anti-Human STAMP2 Monoclonal Antibody (Catalog # MAB4626, filled histogram) or isotype control antibody (Catalog # MAB0041 , open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B ).

Human STAMP2 MAb (Clone 418714), Mouse IgG2B - MAB4626-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 418714
Detection of STAMP2 in Human STAMP2 Transfected HEK293 Human Cell Line by Flow Cytometry. Human STAMP2 transfected HEK293 human cell line was stained with Mouse Anti-Human STAMP2 Monoclonal Antibody (Catalog # MAB4626, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).

STEAP4 Antibody (OAAF02498) - OAAF02498 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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