STEAP4

Gene Symbol STEAP4
Entrez Gene 79689
Alt Symbol STAMP2, TIARP, TNFAIP9
Species Human
Gene Type protein-coding
Description STEAP family member 4
Other Description metalloreductase STEAP4|six transmembrane prostate protein 2|six-transmembrane epithelial antigen of prostate 4|sixTransMembrane protein of prostate 2|tumor necrosis factor, alpha-induced protein 9|tumor necrosis-alpha-induced adipose-related protein
Swissprots Q8WWB0 Q687X4 Q658Q9 Q9H5R1 Q687X5
Accessions CAJ55791 CAJ90615 CAK32295 EAW76906 EAW76907 Q687X5 AF423422 AAQ04063 AF423423 AAQ04064 AK026806 BAB15559 AK027807 AK307644 AL832955 AL833044 CAH56271 AL833671 BC020600 AAH20600 DA977808 DB162772 DC333286 NM_001205315 NP_001192244 NM_001205316 NP_001192245 NM_024636 NP_078912
Function Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation. {ECO:0000250, ECO:0000269|PubMed:18381574, ECO:0000269|PubMed:18430367, ECO:0000269|PubMed:19660107, ECO:0000269|PubMed:19787193}.
Subcellular Location Cell membrane. Golgi apparatus membrane; Multi-pass membrane protein.
Tissue Specificity Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages. {ECO:0000269|PubMed:15897894, ECO:0000269|PubMed:16227996, ECO:0000269|PubMed:18381574, ECO:0000269|PubMed:18430367, ECO:0000269|PubMed:19289123, ECO:0000269|PubMed:19660107}.

STAMP2 CRISPR/Cas9 KO Plasmid (h) - sc-418310 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAMP2 HDR Plasmid (h) - sc-418310-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAMP2 Double Nickase Plasmid (h) - sc-418310-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAMP2 Double Nickase Plasmid (h2) - sc-418310-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAMP2 CRISPR Activation Plasmid (h) - sc-418310-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAMP2 CRISPR Activation Plasmid (h2) - sc-418310-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAMP2 Lentiviral Activation Particles (h) - sc-418310-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAMP2 Lentiviral Activation Particles (h2) - sc-418310-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAMP2 siRNA (h) - sc-89820 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STAMP2 shRNA Plasmid (h) - sc-89820-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STAMP2 shRNA (h) Lentiviral Particles - sc-89820-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU080371 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20722 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20722 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

STEAP4 siRNA (Human) - CRJ2487 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

STEAP4 - MBS8213980 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human STEAP4 siRNA - orb272988 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

STEAP4 shRNA Plasmid (Human) - CHJ2487 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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