STEAP4

Gene Symbol	STEAP4
Entrez Gene	79689
Alt Symbol	STAMP2, TIARP, TNFAIP9
Species	Human
Gene Type	protein-coding
Description	STEAP family member 4
Other Description	metalloreductase STEAP4|six transmembrane prostate protein 2|six-transmembrane epithelial antigen of prostate 4|sixTransMembrane protein of prostate 2|tumor necrosis factor, alpha-induced protein 9|tumor necrosis-alpha-induced adipose-related protein
Swissprots	Q8WWB0 Q687X4 Q658Q9 Q9H5R1 Q687X5
Accessions	CAJ55791 CAJ90615 CAK32295 EAW76906 EAW76907 Q687X5 AF423422 AAQ04063 AF423423 AAQ04064 AK026806 BAB15559 AK027807 AK307644 AL832955 AL833044 CAH56271 AL833671 BC020600 AAH20600 DA977808 DB162772 DC333286 NM_001205315 NP_001192244 NM_001205316 NP_001192245 NM_024636 NP_078912
Function	Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation. {ECO:0000250, ECO:0000269|PubMed:18381574, ECO:0000269|PubMed:18430367, ECO:0000269|PubMed:19660107, ECO:0000269|PubMed:19787193}.
Subcellular Location	Cell membrane. Golgi apparatus membrane; Multi-pass membrane protein.
Tissue Specificity	Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages. {ECO:0000269|PubMed:15897894, ECO:0000269|PubMed:16227996, ECO:0000269|PubMed:18381574, ECO:0000269|PubMed:18430367, ECO:0000269|PubMed:19289123, ECO:0000269|PubMed:19660107}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human STEAP4 protein fragment - ab177658 from Abcam Category Protein Source E. coli Species Human

STEAP4 Antibody Blocking Peptide - LS-E17998 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

STEAP4 Antibody Blocking Peptide - LS-E30383 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

STEAP4 Antibody Blocking Peptide - LS-E26436 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

STEAP4 Antibody Blocking Peptide - LS-E29752 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

STAMP2/STEAP4 Peptide - NBP1-76392PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

STEAP4 Blocking Peptide - 33R-1165 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

STEAP4 Peptide - AC21-1275-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

STEAP4 (1-152, His-tag) - AR51413PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

STEAP4 (1-152, His-tag) - AR51413PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

STEAP4 control peptide - AP26183CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

STEAP4, 1-152aa Human, His tag, E.coli - 01-P2593 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

STEAP4 Peptide - 46-442P from ProSci Category Peptide Species Human

STEAP4 Peptide - 4313P from ProSci Category Peptide Species Human

STEAP4 fusion protein - ag2545 from Proteintech Group Category Protein Source E. coli-derived, T-GST Species Human

STEAP4, 1-152aa Human, His tag, E.coli - GWB-ATG0C3 from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human STEAP4, His-tagged - STEAP4-5097H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human STEAP family member 4, His-tagged - STEAP4-496H from Creative Biomart Category Protein Source E.coli Species Human

STEAP4, 1-152aa, Human, His tag, E.coli (Denatured) - ATGP2593 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

STEAP4 - TP316917 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

STEAP4/Dudulin4, Peptide - MBS426997 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog

STEAP4 Blocking Peptide - abx162050 from Abbexa Category Peptide Species Human, Monkey, Pig

Human STEAP4 protein - orb260119 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

STEAP4 Peptide, Human - M34GP15296H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human Metalloreductase STEAP4 - PHS32593 from AssayPro Prices $80.00 Sizes 20 µg Source STEAP4, 1-152 aa, Human, His tag, E.coli (Denatured) Species Human

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