MARCH4

Gene Symbol MARCH4
Entrez Gene 57574
Alt Symbol MARCH-IV, RNF174
Species Human
Gene Type protein-coding
Description membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
Other Description E3 ubiquitin-protein ligase MARCH4|RING finger protein 174|membrane-associated RING finger protein 4|membrane-associated RING-CH protein IV
Swissprots Q4KMN7 Q9P2E8 Q86WR8
Accessions EAW70566 Q9P2E8 AB037820 BAA92637 AL353945 AW051292 BC048793 AAH48793 BC098448 AAH98448 EU832625 ACE87716 EU832698 ACE87030 U79281 XM_011511523 XP_011509825 NM_020814 NP_065865
Function E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. {ECO:0000269|PubMed:14722266}.
Subcellular Location Golgi apparatus membrane {ECO:0000269|PubMed:14722266}; Multi-pass membrane protein {ECO:0000269|PubMed:14722266}.
Tissue Specificity Expressed in brain and placenta. {ECO:0000269|PubMed:14722266}.

MARCH4 (C-12) - sc-107712 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MARCH4 (D-17) - sc-107713 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MARCH4 (D-17): sc-107713. Western blot analysis of MARCH4 expression in HeLa whole cell lysate.

MARCH4 (E-15) - sc-107714 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MARCH4 (E-15): sc-107714. Western blot analysis of MARCH4 expression in Jurkat whole cell lysate.

Anti-MARCH4 antibody - ab77417 from Abcam

Prices $242.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-MARCH4 antibody - C-terminal - ab171661 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-MARCH4 antibody - C-terminal (ab171661) at 1/100 dilution + Jurkat cell lysate at 35 µg

Anti-RNF174 / MARCH4 Antibody (aa300-350) IHC-plus™ - LS-B1796 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MARCH4 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1796 concentration 5 ug/ml.

Anti-RNF174 / MARCH4 Antibody (aa138-149) - LS-C61764 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-RNF174 / MARCH4 Antibody (aa302-331, AP) - LS-C237396 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF174 / MARCH4 Antibody (aa302-331, Biotin) - LS-C237397 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF174 / MARCH4 Antibody (aa302-331, APC) - LS-C237398 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF174 / MARCH4 Antibody (aa302-331, FITC) - LS-C237399 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF174 / MARCH4 Antibody (aa302-331, PE) - LS-C237403 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF174 / MARCH4 Antibody (aa302-331, Azide-free, HRP) - LS-C248765 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF174 / MARCH4 Antibody (aa301-331) - LS-C322851 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF174 / MARCH4 Antibody (aa301-350) - LS-C119931 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human brain tissue, using MARCH4 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-RNF174 / MARCH4 Antibody (aa36-85) - LS-C102018 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MARCH4 antibody LS-C102018 Western blot of HeLa lysate.

Anti-RNF174 / MARCH4 Antibody (aa302-331) - LS-C158099 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
MARCH4 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MARCH4 antibody detected the MARCH4 protein (arrow).

MARCH4 Antibody - NBP2-24502 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: MARCH4 Antibody [NBP2-24502] - Analysis of human RNF174 in Jurkat cell lysate in the 1) absence and 2) presence of immunizing peptide using this antibody at 5 ug/ml.

MARCH4 Antibody - NBP1-91639 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: MARCH4 Antibody [NBP1-91639] - Staining of human cerebellum shows strong cytoplasmic and nuclear positivity in Purkinje cells.

MARCH4 Antibody - H00057574-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

MARCH4 Antibody - NB100-93416 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

MARCH4 Polyclonal Antibody - bs-9338R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MARCH4 antibody produced in rabbit - HPA014348 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MARCH4: <B>Cat. No. HPA014348</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human cerebellum shows strong cytoplasmic and nuclear positivity in Purkinje cells.

Anti-MARCH4, C-Terminal antibody produced in rabbit - SAB4502517 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MARCH4, C-Terminal: <B>Cat. No. SAB4502517</B>: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-MARCH4, C-Terminal antibody. Cells on the left were treated with the Anti-MARCH4, C-Terminal antibody. Cells on the right (negative control) were treated with both Anti-MARCH4, C-Terminal antibody and the synthesized immunogen peptide.

MARCH4 Antibody - N-terminal region (ARP43280_P050) - ARP43280_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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