MARCH4

Gene Symbol MARCH4
Entrez Gene 57574
Alt Symbol MARCH-IV, RNF174
Species Human
Gene Type protein-coding
Description membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
Other Description E3 ubiquitin-protein ligase MARCH4|RING finger protein 174|membrane-associated RING finger protein 4|membrane-associated RING-CH protein IV
Swissprots Q4KMN7 Q9P2E8 Q86WR8
Accessions EAW70566 Q9P2E8 AB037820 BAA92637 AL353945 AW051292 BC048793 AAH48793 BC098448 AAH98448 EU832625 ACE87716 EU832698 ACE87030 U79281 XM_011511523 XP_011509825 NM_020814 NP_065865
Function E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. {ECO:0000269|PubMed:14722266}.
Subcellular Location Golgi apparatus membrane {ECO:0000269|PubMed:14722266}; Multi-pass membrane protein {ECO:0000269|PubMed:14722266}.
Tissue Specificity Expressed in brain and placenta. {ECO:0000269|PubMed:14722266}.

MARCH4 CRISPR/Cas9 KO Plasmid (h) - sc-412839 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH4 HDR Plasmid (h) - sc-412839-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH4 Double Nickase Plasmid (h) - sc-412839-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH4 Double Nickase Plasmid (h2) - sc-412839-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH4 CRISPR Activation Plasmid (h) - sc-412839-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH4 CRISPR Activation Plasmid (h2) - sc-412839-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH4 Lentiviral Activation Particles (h) - sc-412839-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH4 Lentiviral Activation Particles (h2) - sc-412839-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH4 siRNA (h) - sc-94955 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MARCH4 shRNA Plasmid (h) - sc-94955-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MARCH4 shRNA (h) Lentiviral Particles - sc-94955-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MARCH4 RNAi - H00057574-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU007841 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13033 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13033 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09559 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09559

MARCH4 siRNA (Human) - CRJ1549 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MARCH4 (NM_020814.2) - SHH338275 from Creative biogene

Category siRNA
Species Reactivities Human

Human MARCH4 siRNA - orb272050 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MARCH4 shRNA Plasmid (Human) - CHJ1549 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MARCH4 miRNA 3'UTR clone - MiUTR3H-09845 from Creative biogene

Species Reactivities Human
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