ATF6

Gene Symbol	ATF6
Entrez Gene	22926
Alt Symbol	ATF6A
Species	Human
Gene Type	protein-coding
Description	activating transcription factor 6
Other Description	cAMP-dependent transcription factor ATF-6 alpha|cyclic AMP-dependent transcription factor ATF-6 alpha
Swissprots	O15139 Q5VW62 Q9UEC9 Q6IPB5 P18850
Accessions	EAW90694 P18850 AB015856 BAA34722 AB208929 BAD92166 AF005887 AAB64434 AF088035 AK025316 AK290498 BAF83187 BC014969 AAH14969 BC071997 AAH71997 BC166676 AAI66676 BM683233 BP380917 BX538263 XM_006711224 XP_006711287 XM_011509308 XP_011507610 XM_011509309 XP_011507611 XM_011509310 XP_011507612 NM_007348 NP_031374
Function	Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. {ECO:0000269|PubMed:11158310, ECO:0000269|PubMed:11779464}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Tissue Specificity	Ubiquitous.
Top Pathways	Alzheimer's disease, Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human ATF6 peptide - ab39927 from Abcam Category Peptide Prices $181.00 Sizes 50 µg Species Human

Human ATF6 peptide - ab92653 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human ATF6 protein fragment - ab131846 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

ATF6 Antibody Blocking Peptide - LS-E30206 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ATF6 Antibody Blocking Peptide - LS-E30207 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ATF6 Antibody Blocking Peptide - LS-E11288 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ATF6 Antibody Blocking Peptide - LS-E11074 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ATF6 Antibody Blocking Peptide - LS-E9719 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ATF6 Protein - H00022926-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ATF6 Protein - H00022926-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ATF6 Blocking Peptide - NBP1-77251PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

ATF6 Blocking Peptide - NBP1-76675PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

ATF6-Antibody-Center-Blocking-Peptide - BP8681c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human ATF6 Protein - abx065129 from Abbexa Category Protein Source E.coli Species Human

ATF6 Peptide - AC21-2956-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ATF6 alpha - H00022926-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ATF6 alpha - H00022926-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ATF6 alpha - H00022926-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ATF6 alpha - H00022926-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ATF6 alpha Control Peptide - AP30088CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

ATF6 alpha Control Peptide - AP30089CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

ATF6 Peptide - 3683P from ProSci Category Peptide Species Human

ATF6 Peptide - 3681P from ProSci Category Peptide Species Human

ATF6 fusion protein - ag21456 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human ATF6, His-tagged - ATF6-26190TH from Creative Biomart Category Protein Source E. coli

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