ATF6

Gene Symbol ATF6
Entrez Gene 22926
Alt Symbol ATF6A
Species Human
Gene Type protein-coding
Description activating transcription factor 6
Other Description cAMP-dependent transcription factor ATF-6 alpha|cyclic AMP-dependent transcription factor ATF-6 alpha
Swissprots O15139 Q5VW62 Q9UEC9 Q6IPB5 P18850
Accessions EAW90694 P18850 AB015856 BAA34722 AB208929 BAD92166 AF005887 AAB64434 AF088035 AK025316 AK290498 BAF83187 BC014969 AAH14969 BC071997 AAH71997 BC166676 AAI66676 BM683233 BP380917 BX538263 XM_006711224 XP_006711287 XM_011509308 XP_011507610 XM_011509309 XP_011507611 XM_011509310 XP_011507612 NM_007348 NP_031374
Function Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. {ECO:0000269|PubMed:11158310, ECO:0000269|PubMed:11779464}.
Subcellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Tissue Specificity Ubiquitous.
Top Pathways Alzheimer's disease, Protein processing in endoplasmic reticulum

ATF-6α CRISPR/Cas9 KO Plasmid (h) - sc-400259 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-6α HDR Plasmid (h) - sc-400259-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-6α Double Nickase Plasmid (h) - sc-400259-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-6α Double Nickase Plasmid (h2) - sc-400259-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-6α CRISPR Activation Plasmid (h) - sc-400259-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-6α CRISPR Activation Plasmid (h2) - sc-400259-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-6α Lentiviral Activation Particles (h) - sc-400259-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-6α Lentiviral Activation Particles (h2) - sc-400259-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-6α siRNA (h) - sc-37699 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATF-6α shRNA Plasmid (h) - sc-37699-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATF-6α shRNA (h) Lentiviral Particles - sc-37699-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATF6 RNAi - H00022926-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU015441 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3637 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

ATF6 siRNA (Human) - CRH7877 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATF6 - MBS8239944 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ATF6 (NM_007348.3) - SHH241954 from Creative biogene

Category siRNA
Species Reactivities Human

ATF6 shRNA Plasmid (Human) - CHH7877 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ATF6 miRNA 3'UTR clone - MiUTR3H-07774 from Creative biogene

Species Reactivities Human
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