Gene Symbol | LAMC2 |
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Entrez Gene | 3918 |
Alt Symbol | B2T, BM600, CSF, EBR2, EBR2A, LAMB2T, LAMNB2 |
Species | Human |
Gene Type | protein-coding |
Description | laminin, gamma 2 |
Other Description | BM600-100kDa|CSF 140 kDa subunit|cell-scattering factor 140 kDa subunit|epiligrin subunit gamma|kalinin subunit gamma|ladsin 140 kDa subunit|laminin B2t chain|laminin subunit gamma-2|large adhesive scatter factor 140 kDa subunit|nicein subunit gamma |
Swissprots | Q02536 Q14941 Q13752 Q2M1N2 Q5VYE8 Q13753 Q02537 Q14DF7 |
Accessions | AAC50456 AAC50457 EAW91146 EAW91147 Q13753 AK296944 BAG59493 AK307945 BC112286 AAI12287 BC113378 AAI13379 BC143653 X73902 CAA52108 Z15008 CAA78728 Z15009 CAA78729 NM_005562 NP_005553 NM_018891 NP_061486 |
Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell- scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells. {ECO:0000269|PubMed:8265624}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component. |
Tissue Specificity | The large variant is expressed only in specific epithelial cells of embryonic and neonatal tissues. In 17-week old embryo the small variant is found in cerebral cortex, lung, and distal tubes of kidney, but not in epithelia except for distal tubuli. |
Top Pathways | Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Toxoplasmosis |
Active human GMCSF + IL3 full length protein - ab73275 from Abcam
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Human LAMC2 protein fragment - ab158812 from Abcam
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Human Laminin 5 alpha 3 protein fragment - ab158810 from Abcam
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LAMC2 / Laminin Gamma 2 Antibody Blocking Peptide - LS-E2863 from LifeSpan Bioscience
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Recombinant Human LAMC2 Protein - H00003918-Q01 from Novus Biologicals
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LAMC2-Antibody-Center-Blocking-peptide - BP13984c from Abgent, a WuXi AppTec company
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laminin gamma 2 blocking peptide - GTX89410-PEP from GeneTex
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GMCSF protein - 30R-3029 from Fitzgerald
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Human Laminin Gamma 2 Protein - abx067711 from Abbexa
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Laminin gamma 2 / Laminin-5 - H00003918-Q01-10 from Acris Antibodies
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Laminin gamma 2 / Laminin-5 - H00003918-Q01-25 from Acris Antibodies
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LAMC2 fusion protein - ag19181 from Proteintech Group
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Recombinant Human GM-CSF Protein - BP000176-C040 from Syd Labs
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Recombinant Laminin Gamma 2 (LAMC2) - RPC083Hu01 from Uscn Life Science Inc.
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Recombinant Laminin Gamma 2 (LAMC2) - RPC083Hu02 from Uscn Life Science Inc.
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Recombinant Laminin Gamma 2 (LAMC2) - RPC083Hu03 from Uscn Life Science Inc.
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Recombinant Laminin Gamma 2 (LAMC2) - RPC083Mu01 from Uscn Life Science Inc.
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Recombinant Laminin Gamma 2 (LAMC2) - RPC083Ra01 from Uscn Life Science Inc.
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Recombinant Laminin Gamma 2 (LAMC2) - RPC083Hu01 from Cloud-clone
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Recombinant Laminin Gamma 2 (LAMC2) - RPC083Hu02 from Cloud-clone
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Recombinant Laminin Gamma 2 (LAMC2) - RPC083Hu03 from Cloud-clone
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Recombinant Human Laminin subunit gamma-2(LAMC2) ,partial - CSB-YP618803HU CSB-EP618803HU CSB-BP618803HU CSB-MP618803HU from Cusabio
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Laminin gamma 2 / Laminin-5 (transcript variant 2) - TP318516 from Acris Antibodies
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Laminin gamma 2 / Laminin-5 (transcript variant 1) - TP322076 from Acris Antibodies
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LAMC2 Recombinant Protein Antigen - NBP1-88576PEP from Novus Biologicals
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