Gene Symbol | LAMC2 |
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Entrez Gene | 3918 |
Alt Symbol | B2T, BM600, CSF, EBR2, EBR2A, LAMB2T, LAMNB2 |
Species | Human |
Gene Type | protein-coding |
Description | laminin, gamma 2 |
Other Description | BM600-100kDa|CSF 140 kDa subunit|cell-scattering factor 140 kDa subunit|epiligrin subunit gamma|kalinin subunit gamma|ladsin 140 kDa subunit|laminin B2t chain|laminin subunit gamma-2|large adhesive scatter factor 140 kDa subunit|nicein subunit gamma |
Swissprots | Q02536 Q14941 Q13752 Q2M1N2 Q5VYE8 Q13753 Q02537 Q14DF7 |
Accessions | AAC50456 AAC50457 EAW91146 EAW91147 Q13753 AK296944 BAG59493 AK307945 BC112286 AAI12287 BC113378 AAI13379 BC143653 X73902 CAA52108 Z15008 CAA78728 Z15009 CAA78729 NM_005562 NP_005553 NM_018891 NP_061486 |
Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell- scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells. {ECO:0000269|PubMed:8265624}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component. |
Tissue Specificity | The large variant is expressed only in specific epithelial cells of embryonic and neonatal tissues. In 17-week old embryo the small variant is found in cerebral cortex, lung, and distal tubes of kidney, but not in epithelia except for distal tubuli. |
Top Pathways | Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Toxoplasmosis |
Laminin γ-2 (B-2) - sc-25341 from Santa Cruz Biotechnology
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Laminin γ-2 (C-20) - sc-7652 from Santa Cruz Biotechnology
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Laminin γ-2 (E-1) - sc-55457 from Santa Cruz Biotechnology
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Laminin γ-2 (E-6) - sc-28330 from Santa Cruz Biotechnology
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Laminin γ-2 (G-16) - sc-31092 from Santa Cruz Biotechnology
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Laminin γ-2 (G-7) - sc-393225 from Santa Cruz Biotechnology
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Laminin γ-2 (H-183) - sc-20776 from Santa Cruz Biotechnology
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Laminin γ-2 (H-8) - sc-393502 from Santa Cruz Biotechnology
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Anti-LAMC2 antibody - ab116660 from Abcam
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Anti-LAMC2 antibody - ab96327 from Abcam
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Anti-LAMC2 antibody - C-terminal - ab190675 from Abcam
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Anti-LAMC2 / Laminin Gamma 2 Antibody (aa940-970, AP) - LS-C261662 from LifeSpan Bioscience
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Anti-LAMC2 / Laminin Gamma 2 Antibody (aa940-970, APC) - LS-C261663 from LifeSpan Bioscience
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Anti-LAMC2 / Laminin Gamma 2 Antibody (aa940-970, Biotin) - LS-C261664 from LifeSpan Bioscience
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Anti-LAMC2 / Laminin Gamma 2 Antibody - LS-C152903 from LifeSpan Bioscience
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Anti-LAMC2 / Laminin Gamma 2 Antibody (aa940-970, Azide-free, HRP) - LS-C261666 from LifeSpan Bioscience
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Anti-LAMC2 / Laminin Gamma 2 Antibody (aa940-970, PE) - LS-C261667 from LifeSpan Bioscience
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Anti-LAMC2 / Laminin Gamma 2 Antibody (aa940-970, FITC) - LS-C261665 from LifeSpan Bioscience
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Anti-LAMC2 / Laminin Gamma 2 Antibody (aa972-1191, FITC) - LS-C302534 from LifeSpan Bioscience
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Anti-LAMC2 / Laminin Gamma 2 Antibody (aa972-1191, Biotin) - LS-C299964 from LifeSpan Bioscience
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Anti-LAMC2 / Laminin Gamma 2 Antibody (aa940-970) - LS-C329757 from LifeSpan Bioscience
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Anti-LAMC2 / Laminin Gamma 2 Antibody (aa1003-1192) - LS-C314890 from LifeSpan Bioscience
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Anti-LAMC2 / Laminin Gamma 2 Antibody (aa972-1191) - LS-C295092 from LifeSpan Bioscience
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Anti-LAMC2 / Laminin Gamma 2 Antibody (aa28-196) - LS-C295093 from LifeSpan Bioscience
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Anti-LAMC2 / Laminin Gamma 2 Antibody (aa941-970) - LS-C165673 from LifeSpan Bioscience
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