| Gene Symbol |
STAT5B
|
| Entrez Gene |
6777
|
| Alt Symbol |
STAT5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
signal transducer and activator of transcription 5B
|
| Other Description |
transcription factor STAT5B
|
| Swissprots |
P51692 Q8WWS8
|
| Accessions |
CAD19638 CAG32954 EAW60817 P51692 AB208920 BAD92157 AK308163 AL040162 AL080218 BC020868 AAH20868 BC029072 BC065227 AAH65227 EU446501 ABZ92030 U47686 AAC50491 U48730 AAC50485 XM_005257625 XP_005257682 XM_005257626 XP_005257683 NM_012448 NP_036580
|
| Function |
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. {ECO:0000269|PubMed:11773439}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocated into the nucleus in response to phosphorylation. {ECO:0000250}.
|
| Top Pathways |
Chemokine signaling pathway, Prolactin signaling pathway, Viral carcinogenesis, Measles, HTLV-I infection
|
