Gene Symbol | STAT5B |
---|---|
Entrez Gene | 6777 |
Alt Symbol | STAT5 |
Species | Human |
Gene Type | protein-coding |
Description | signal transducer and activator of transcription 5B |
Other Description | transcription factor STAT5B |
Swissprots | P51692 Q8WWS8 |
Accessions | CAD19638 CAG32954 EAW60817 P51692 AB208920 BAD92157 AK308163 AL040162 AL080218 BC020868 AAH20868 BC029072 BC065227 AAH65227 EU446501 ABZ92030 U47686 AAC50491 U48730 AAC50485 XM_005257625 XP_005257682 XM_005257626 XP_005257683 NM_012448 NP_036580 |
Function | Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. {ECO:0000269|PubMed:11773439}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocated into the nucleus in response to phosphorylation. {ECO:0000250}. |
Top Pathways | Chemokine signaling pathway, Prolactin signaling pathway, Viral carcinogenesis, Measles, HTLV-I infection |