STAT5B

Gene Symbol STAT5B
Entrez Gene 6777
Alt Symbol STAT5
Species Human
Gene Type protein-coding
Description signal transducer and activator of transcription 5B
Other Description transcription factor STAT5B
Swissprots P51692 Q8WWS8
Accessions CAD19638 CAG32954 EAW60817 P51692 AB208920 BAD92157 AK308163 AL040162 AL080218 BC020868 AAH20868 BC029072 BC065227 AAH65227 EU446501 ABZ92030 U47686 AAC50491 U48730 AAC50485 XM_005257625 XP_005257682 XM_005257626 XP_005257683 NM_012448 NP_036580
Function Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. {ECO:0000269|PubMed:11773439}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocated into the nucleus in response to phosphorylation. {ECO:0000250}.
Top Pathways Chemokine signaling pathway, Prolactin signaling pathway, Viral carcinogenesis, Measles, HTLV-I infection

Stat5 (C-8) - sc-377069 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Stat5 (C-8): sc-377069. Western blot analysis of Stat5b expression in non-transfected: sc-117752 (A) and human Stat5b transfected: sc-116946 (B) 293T whole cell lysates.

Stat5b (G-2) - sc-1656 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Stat5b (G-2): sc-1656. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon carcinoma tissue showing nuclear staining.

Anti-STAT5b [EPR16671] antibody - ab178941 from Abcam

Prices $99.00, $357.00
Sizes 10 µl, 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16671
Immunofluorescent analysis of 4% paraformaldehyde-fixed HeLa (Human epithelial cells from cervix adenocarcinoma) cells labeling STAT5b with ab178941 at 1/100 dilution. The cells were permeabilised with 0.1% Triton X-100. Goat anti-rabbit IgG (Alexa Fluor® 488) (ab150077) at 1/200 dilution was used as the secondary antibody (green). Nuclear and cytoplasm staining is detected. The nuclear counter stain is DAPI (blue). Tubulin is detected with ab7291 (Tubulin mouse mAb) at 1/500 and ab150120 (AlexaFluor®594 Goat anti-Mouse secondary) at 1/400 dilution (red).  The negative controls are as follows;1. ab178941 at 1/100 dilution followed by Goat anti mouse IgG (Alexa Fluor®594) at 1/400 dilution.2. ab7291 (anti-Tubulin mouse mAb) at 1/500 dilution followed by Goat anti rabbit IgG (Alexa Fluor®488) ar 1/200 dilution.  

Anti-STAT5b (phospho S731) antibody - ab52211 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-STAT5b (phospho S731) antibody (ab52211) at 1/500 dilutionLane 1 : Extracts from RAW264.7 cells treated with EGF (200ng/ml, 30min) Lane 2 : Extracts from RAW264.7 cells treated with EGF (200ng/ml, 30min), ab52211 was pre-incubated with immunising (blocking) peptide

Anti-STAT5b (phospho S731) antibody - ab195863 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-STAT5b (phospho S731) antibody (ab195863) at 1/500 dilutionLane 1 : RAW264.7 whole cell lysate with antigen-specific peptideLane 2 : RAW264.7 whole cell lysateLysates/proteins at 12.5 µg per lane.

Anti-STAT5b antibody - ab76944 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Immunofluorescence analysis of HeLa cells using ab76944 at 10µg/ml.

Anti-STAT5b antibody - ab52162 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-STAT5b antibody (ab52162) at 1/500 dilutionLane 1 : extracts from RAW264.7 cells, treated with EGF (200ng/ml 30min), without immunising peptideLane 2 : extracts from RAW264.7 cells, treated with EGF (200ng/ml 30min), with immunising peptide

Anti-STAT5b antibody - ab57825 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-STAT5b antibody - ab57826 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-STAT5b antibody [5B3] - ab106075 from Abcam

Host Mouse
Clonality Monoclonal
Clone 5B3
All lanes : Anti-STAT5b antibody [5B3] (ab106075) at 1/200 dilutionLane 1 : HeLa cell lysateLane 2 : K562 cell lysateLane 3 : NIH 3T3 cell lysateLane 4 : C6 cell lysateLane 5 : HK293 cell lysateLane 6 : Jurkat cell lysateLane 7 : HL60 cell lysate

Anti-STAT5b antibody [EPR16671] (Alexa Fluor® 488) - ab199767 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16671
ab199767 staining STAT5b in HeLa cells. The cells were fixed with 4% formaldehyde (10 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab at a 1/100 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at a 1/250 dilution (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).This product also gave a positive signal under the same testing conditions in HeLa cells fixed with 100% methanol (5 min).

Anti-STAT5b antibody [EPR16671] (Alexa Fluor® 647) - ab199846 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16671
ab199846 staining STAT5b in HeLa cells. The cells were fixed with 4% formaldehyde (10 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab at a 1/100 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at a 1/250 dilution (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).This product also gave a positive signal under the same testing conditions in HeLa cells fixed with 100% methanol (5 min).

Anti-STAT5b antibody [EPR16671] (HRP) - ab199570 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16671
All lanes : Anti-STAT5b antibody [EPR16671] (HRP) (ab199570) at 1/5000 dilutionLane 1 : K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell LysateLane 2 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 3 : NIH 3T3 (Mouse embryonic fibroblast cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.developed using the ECL techniquePerformed under reducing conditions.

Anti-STAT5b antibody [STAT2C321] - ab50762 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone STAT2C321
Anti-STAT5b antibody [STAT2C321] (ab50762) + immunized recombinant protien

Anti-STAT5b antibody - C-terminal - ab135762 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human breast carcinoma tissue labelling STAT5b with ab135762 at 1/50 dilution followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-STAT5b antibody - N-terminal - ab189161 from Abcam

Prices $407.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded Human breast sections labeling STAT5b ab189161 at a 1/50 dilution, followed by alkaline phosphatase-streptavidin and chromogen.

Anti-STAT5B Antibody (N-Terminus) IHC-plus™ - LS-B1679 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-STAT5B antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1679 dilution 1:50.

Anti-STAT5B Antibody (clone 2D1) IHC-plus™ - LS-B5541 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2D1
Anti-STAT5B antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5541 concentration 5 ug/ml.

Anti-STAT5B Antibody (clone 5D6) IHC-plus™ - LS-B5540 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 5D6
Anti-STAT5B antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5540 concentration 5 ug/ml.

Anti-STAT5B Antibody - LS-C330891 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded Breast cancer using STAT5B Antibody.

Anti-STAT5B Antibody (aa180-229) IHC-plus™ - LS-B4572 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STAT5B antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4572 concentration 5 ug/ml.

Anti-STAT5B Antibody (N-Terminus) IHC-plus™ - LS-B4002 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STAT5B antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4002 concentration 5 ug/ml.

Anti-STAT5B Antibody (aa776-786) - LS-C10421 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-STAT5B Antibody (C-Terminus) - LS-C10425 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-STAT5B Antibody (C-Terminus) - LS-C10426 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
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