ARHGAP17

Gene Symbol	ARHGAP17
Entrez Gene	55114
Alt Symbol	MST066, MST110, MSTP038, MSTP066, MSTP110, NADRIN, PP367, PP4534, RICH-1, RICH1, WBP15
Species	Human
Gene Type	protein-coding
Description	Rho GTPase activating protein 17
Other Description	RhoGAP interacting with CIP4 homologs 1|neuron-associated developmentally regulated protein|rho GTPase-activating protein 17|rho-type GTPase-activating protein 17
Swissprots	Q9BVF6 Q96KS3 Q7Z2F2 Q9H8U5 Q6ZUS4 Q96SS8 Q96KS2 Q8NDG2 Q9NW54 A8K6M6 Q68EM7
Accessions	EAW55778 EAW55779 EAW55780 Q68EM7 AF113218 AAG39289 AF163257 AAQ13586 AF173885 AAQ13632 AF258560 AAG23763 AF258580 AAG23783 AJ306731 CAC37948 AJ306732 CAC37949 AK001170 AK023281 BAB14506 AK027567 BAB55203 AK094886 AK125358 BAC86144 AK291691 BAF84380 AK301055 BAG62665 AK301500 BAG63011 AL833975 CAD38819 BC001241 AAH01241 BC080195 AAH80195 BI906519 BU187683 XM_011545873 XP_011544175 XM_011545874 XP_011544176 XM_011545875 XP_011544177 XM_011545876 XP_011544178 XM_011545877 XP_011544179 XM_011545878 XP_011544180 XR_950809 XR_950810 XR_950811 NM_001006634 NP_001006635 NM_018054 NP_060524
Function	Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1. {ECO:0000269|PubMed:11431473, ECO:0000269|PubMed:16678097}.
Subcellular Location	Membrane; Peripheral membrane protein. Cytoplasm. Cell junction, tight junction. Note=Associates with membranes and concentrates at sites of cell-cell contact.
Tissue Specificity	Ubiquitously expressed. Expressed at higher level in heart and placenta. {ECO:0000269|PubMed:11431473}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ARHGAP17 full length protein - ab132846 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human ARHGAP17 protein fragment - ab127224 from Abcam Category Protein Prices $364.00 Sizes 50 µg Source E. coli Species Human

ARHGAP17 / NADRIN Antibody Blocking Peptide - LS-E472 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ARHGAP17 Protein - H00055114-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ARHGAP17-Antibody-N-term-Blocking-peptide - BP10759a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ARHGAP17 peptide - orb218563 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Drosophila

ARHGAP17 Blocking Peptide - abx063894 from Abbexa Category Peptide Species Human, Dog

ARHGAP17 - H00055114-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ARHGAP17 - H00055114-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ARHGAP17 fusion protein - ag2998 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ARHGAP17 Blocking Peptide - CBP2700 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Dog

Recombinant Human Rho GTPase-activating protein 17(ARHGAP17) ,partial - CSB-YP737877HU CSB-EP737877HU CSB-BP737877HU CSB-MP737877HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ARHGAP17 (transcript variant 1) - TP309915 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ARHGAP17 Recombinant Protein Antigen - NBP1-83870PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ARHGAP17 Peptide, Human - M34GP00847H from Creative Peptides Category Peptide Source Synthetic. Species Human

Rho GTPase-activating protein 17 (ARHGAP17), partial, Recombinant Protein - MBS1314144 from MyBioSource Category Protein Prices $1,675.00, $1,835.00, $1,975.00, $2,090.00, $2,285.00, $2,330.00, $2,610.00, $2,885.00, $3,305.00, $4,125.00 Sizes 50 µg (Baculovirus), 500 µg (E-Coli), 500 µg (Yeast), 100 µg (Baculovirus), 1 mg (E-Coli), 50 µg (Mammalian-Cell), 1 mg (Yeast), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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