ARHGAP17

Gene Symbol ARHGAP17
Entrez Gene 55114
Alt Symbol MST066, MST110, MSTP038, MSTP066, MSTP110, NADRIN, PP367, PP4534, RICH-1, RICH1, WBP15
Species Human
Gene Type protein-coding
Description Rho GTPase activating protein 17
Other Description RhoGAP interacting with CIP4 homologs 1|neuron-associated developmentally regulated protein|rho GTPase-activating protein 17|rho-type GTPase-activating protein 17
Swissprots Q9BVF6 Q96KS3 Q7Z2F2 Q9H8U5 Q6ZUS4 Q96SS8 Q96KS2 Q8NDG2 Q9NW54 A8K6M6 Q68EM7
Accessions EAW55778 EAW55779 EAW55780 Q68EM7 AF113218 AAG39289 AF163257 AAQ13586 AF173885 AAQ13632 AF258560 AAG23763 AF258580 AAG23783 AJ306731 CAC37948 AJ306732 CAC37949 AK001170 AK023281 BAB14506 AK027567 BAB55203 AK094886 AK125358 BAC86144 AK291691 BAF84380 AK301055 BAG62665 AK301500 BAG63011 AL833975 CAD38819 BC001241 AAH01241 BC080195 AAH80195 BI906519 BU187683 XM_011545873 XP_011544175 XM_011545874 XP_011544176 XM_011545875 XP_011544177 XM_011545876 XP_011544178 XM_011545877 XP_011544179 XM_011545878 XP_011544180 XR_950809 XR_950810 XR_950811 NM_001006634 NP_001006635 NM_018054 NP_060524
Function Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1. {ECO:0000269|PubMed:11431473, ECO:0000269|PubMed:16678097}.
Subcellular Location Membrane; Peripheral membrane protein. Cytoplasm. Cell junction, tight junction. Note=Associates with membranes and concentrates at sites of cell-cell contact.
Tissue Specificity Ubiquitously expressed. Expressed at higher level in heart and placenta. {ECO:0000269|PubMed:11431473}.

ARHGAP17 (G-6) - sc-514438 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ARHGAP17 (G-6): sc-514438. Western blot analysis of ARHGAP17 expression in non-transfected 293T: sc-117752 (A), human ARHGAP17 transfected 293T: sc-111410 (B), T24 (C) and RT-4 (D) whole cell lysates.

ARHGAP17 (F-18) - sc-160145 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ARHGAP17 (F-18): sc-160145. Western blot analysis of ARHGAP17 expression in HeLa whole cell lysate.

ARHGAP17 (S-13) - sc-160146 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ARHGAP17 (S-13): sc-160146. Western blot analysis of ARHGAP17 expression in HeLa whole cell lysate.

Anti-ARHGAP17 antibody - ab74454 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ARHGAP17 antibody (ab74454) at 1/500 dilutionLane 1 : extracts from LOVO cellsLane 2 : extracts from LOVO cells with immunizing peptide at 5 µgLysates/proteins at 15 µg per lane.

Anti-ARHGAP17 antibody - ab140170 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ARHGAP17 antibody (ab140170) at 1/1000 dilution + Lovo cell lysate

Anti-ARHGAP17 / NADRIN Antibody (aa41-70, AP) - LS-C251635 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP17 / NADRIN Antibody (aa41-70, Biotin) - LS-C251637 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP17 / NADRIN Antibody (aa41-70, APC) - LS-C251636 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP17 / NADRIN Antibody (aa41-70, FITC) - LS-C251638 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP17 / NADRIN Antibody (aa41-70, Azide-free, HRP) - LS-C251639 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP17 / NADRIN Antibody (aa331-380) - LS-C120326 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from LOVO cells, using RHG17 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-ARHGAP17 / NADRIN Antibody (aa41-70, PE) - LS-C251640 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP17 / NADRIN Antibody (aa44-74) - LS-C319572 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP17 / NADRIN Antibody (aa2-195) - LS-C179084 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP17 / NADRIN Antibody (aa44-74) - LS-C156467 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ARHGAP17 Antibody western blot of K562 cell line lysates (35 ug/lane). The ARHGAP17 antibody detected the ARHGAP17 protein (arrow).

ARHGAP17 Antibody - NBP1-83870 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ARHGAP17 Antibody [NBP1-83870] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

ARHGAP17 Polyclonal Antibody - bs-2304R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RHG17 antibody produced in rabbit - SAB4502296 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RHG17: <B>Cat. No. SAB4502296</B>: Immunoblotting analysis of extracts from LOVO cells, using Anti-RHG17 antibody. The lane on the left was treated with the Anti-RHG17 antibody. The lane on the right (negative control) was treated with both Anti-RHG17 antibody and the synthesized immunogen peptide.

Anti-ARHGAP17 (237-250) antibody produced in rabbit - SAB1102117 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human ARHGAP17 was separated on SDS-PAGE, blotted with Anti-ARHGAP17 (237-250) (<B>Cat. No. SAB1102117</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500 <BR/>2. Antibody dilution 1:500 + ARHGAP17 immunizing peptide (human, 237-250)

Anti-ARHGAP17 antibody produced in rabbit - HPA041703 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ARHGAP17: <B>Cat. No. HPA041703</B>: Immunohistochemical staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.

ARHGAP17 Antibody - N-terminal region (OAAB00777) - OAAB00777 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

ARHGAP17-Antibody-N-term - AP10759a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
ARHGAP17 Antibody (N-term) (Cat. #AP10759a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ARHGAP17 antibody detected the ARHGAP17 protein (arrow).
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